Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019
It is not well-known if valve replacement outcomes differ in patients with sarcoidosis, especially in aortic valve intervention, where the pressure gradients are physiologically high. In this retrospective study, we included all patients who underwent surgical/transcatheter aortic valve replacement...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Indian Heart Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483225000045 |
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| author | Kunal N. Patel Suryansh Bajaj Monil Majmundar Vidit Majmundar Ankit Agrawal Harshvardhan Zala Rajkumar Doshi Karandeep Singh Avleen Kaur Vyoma N. Patel Karthik Gonuguntla Yasar Sattar Ankur Kalra |
| author_facet | Kunal N. Patel Suryansh Bajaj Monil Majmundar Vidit Majmundar Ankit Agrawal Harshvardhan Zala Rajkumar Doshi Karandeep Singh Avleen Kaur Vyoma N. Patel Karthik Gonuguntla Yasar Sattar Ankur Kalra |
| author_sort | Kunal N. Patel |
| collection | DOAJ |
| description | It is not well-known if valve replacement outcomes differ in patients with sarcoidosis, especially in aortic valve intervention, where the pressure gradients are physiologically high. In this retrospective study, we included all patients who underwent surgical/transcatheter aortic valve replacement from the Nationwide Readmission Database (2016–2019), and then divided them into those with and without sarcoidosis. Logistic and cox proportional hazard regression models were used. In-hospital mortality, stroke, acute kidney injury, paravalvular leak, 30-day pacemaker implantation, and 30-day heart failure readmission were similar in patients with and without sarcoidosis. Thus, sarcoidosis did not affect the clinical outcomes in patients undergoing aortic valve replacement. Further prospective studies are needed in this patient subgroup to support clinical decision-making. |
| format | Article |
| id | doaj-art-78e1d714585c41f0b42aae28cd890af9 |
| institution | Kabale University |
| issn | 0019-4832 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj-art-78e1d714585c41f0b42aae28cd890af92025-08-20T03:44:07ZengElsevierIndian Heart Journal0019-48322025-01-01771454710.1016/j.ihj.2025.01.003Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019Kunal N. Patel0Suryansh Bajaj1Monil Majmundar2Vidit Majmundar3Ankit Agrawal4Harshvardhan Zala5Rajkumar Doshi6Karandeep Singh7Avleen Kaur8Vyoma N. Patel9Karthik Gonuguntla10Yasar Sattar11Ankur Kalra12Department of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USADepartment of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USADepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USADepartment of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USADepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USADepartment of Infectious Disease, Upstate University, Syracuse, NY, USADepartment of Cardiology, St. Joseph's University Medical Center, Paterson, NJ, USADept of Internal Medicine, Government Medical College, Amritsar, Punjab, IndiaDepartment of Gastroenterology, Upstate University, Syracuse, NY, USADepartment of Internal Medicine, Maimonides Medical Center, Brooklyn, NY, USADepartment of Cardiovascular Medicine, West Virginia University, Morgantown, WV, USADepartment of Cardiovascular Medicine, West Virginia University, Morgantown, WV, USAFranciscan Health, Lafayette, IN, USA; Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, IN, USA; Corresponding author. Franciscan Health, 3900 St. Francis Way Ste 200, Lafayette, Indiana, 47905, USA. Tel.: 765-775-2800, Fax: 765-775-2831.It is not well-known if valve replacement outcomes differ in patients with sarcoidosis, especially in aortic valve intervention, where the pressure gradients are physiologically high. In this retrospective study, we included all patients who underwent surgical/transcatheter aortic valve replacement from the Nationwide Readmission Database (2016–2019), and then divided them into those with and without sarcoidosis. Logistic and cox proportional hazard regression models were used. In-hospital mortality, stroke, acute kidney injury, paravalvular leak, 30-day pacemaker implantation, and 30-day heart failure readmission were similar in patients with and without sarcoidosis. Thus, sarcoidosis did not affect the clinical outcomes in patients undergoing aortic valve replacement. Further prospective studies are needed in this patient subgroup to support clinical decision-making.http://www.sciencedirect.com/science/article/pii/S0019483225000045Aortic valve replacementTAVRSAVRSarcoidosisAortic stenosisMortality |
| spellingShingle | Kunal N. Patel Suryansh Bajaj Monil Majmundar Vidit Majmundar Ankit Agrawal Harshvardhan Zala Rajkumar Doshi Karandeep Singh Avleen Kaur Vyoma N. Patel Karthik Gonuguntla Yasar Sattar Ankur Kalra Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 Indian Heart Journal Aortic valve replacement TAVR SAVR Sarcoidosis Aortic stenosis Mortality |
| title | Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 |
| title_full | Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 |
| title_fullStr | Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 |
| title_full_unstemmed | Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 |
| title_short | Impact of sarcoidosis in patients undergoing aortic valve replacement: Insight from nationwide readmission database 2016–2019 |
| title_sort | impact of sarcoidosis in patients undergoing aortic valve replacement insight from nationwide readmission database 2016 2019 |
| topic | Aortic valve replacement TAVR SAVR Sarcoidosis Aortic stenosis Mortality |
| url | http://www.sciencedirect.com/science/article/pii/S0019483225000045 |
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