Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results
Background. Modern preventive vaccination is intended to protect and enhance the health of every person considering age and health issues. Vaccination of children with chronic diseases in our country remains extremely topical and arguable problem that associated with many pending issues for doctors...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2021-12-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/2098 |
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| author | Marina V. Fedoseenko Leyla S. Namazova-Baranova Elena A. Vishneva Svetlana V. Tolstova Arevaluis M. Selvyan Tatiana A. Kaliuzhnaia Firuza Ch. Shakhtakhtinskaya Margarita A. Soloshenko Tatiana E. Privalova Maria V. Fominyh Tatiana E. Zinovyeva |
| author_facet | Marina V. Fedoseenko Leyla S. Namazova-Baranova Elena A. Vishneva Svetlana V. Tolstova Arevaluis M. Selvyan Tatiana A. Kaliuzhnaia Firuza Ch. Shakhtakhtinskaya Margarita A. Soloshenko Tatiana E. Privalova Maria V. Fominyh Tatiana E. Zinovyeva |
| author_sort | Marina V. Fedoseenko |
| collection | DOAJ |
| description | Background. Modern preventive vaccination is intended to protect and enhance the health of every person considering age and health issues. Vaccination of children with chronic diseases in our country remains extremely topical and arguable problem that associated with many pending issues for doctors of various specialties, including those working as primary care specialists.Objective. The aim of the study is to develop major approaches and to prove scientifically the efficacy and safety of preventive vaccination for children with various chronic diseases.Methods. We have conducted comprehensive study of 100 children aged from 1 month to 17 years 11 months. Children were divided into 4 groups according to the specific disease. Vaccinal and infectious history was analyzed. The post-vaccination period was estimated due to the results of the questionnaire completed by parents. Vaccination immunogenicity was estimated based on the results of the level of specific antibodies to various controlled infections (measles, rubella, parotitis, hepatitis B, pertussis, haemophilus influenza type b).Results. Protective titers of antibodies against haemophilus influenza type b were revealed in 96.2% of all examined patients, tetanus and hepatitis B — in 95.2%, against pertussis — in 92.5%, rubella — in 91%, measles — in 87.5%, parotitis — in 71.9%, chickenpox — in 69% children a month after the completed vaccination. The postvaccinal period was characterized as favorable in most patients. Major changes in overall health status occurred after vaccination in 42% of children was the following: subfebrile fever, capriciousness, or fatigue. Local reactions have developed only in 15% of cases.Conclusion. The results of this study have demonstrated the preventive vaccination efficacy and safety in children with various chronic diseases |
| format | Article |
| id | doaj-art-78d563e919ac4bfba10e4c9087ec960c |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2021-12-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-78d563e919ac4bfba10e4c9087ec960c2025-08-20T03:40:10ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892021-12-0118646948210.15690/pf.v18i6.23281857Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study ResultsMarina V. Fedoseenko0Leyla S. Namazova-Baranova1Elena A. Vishneva2Svetlana V. Tolstova3Arevaluis M. Selvyan4Tatiana A. Kaliuzhnaia5Firuza Ch. Shakhtakhtinskaya6Margarita A. Soloshenko7Tatiana E. Privalova8Maria V. Fominyh9Tatiana E. Zinovyeva10Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; Belgorod National Research UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityResearch Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical UniversityMoscow Regional Perinatal CenterBackground. Modern preventive vaccination is intended to protect and enhance the health of every person considering age and health issues. Vaccination of children with chronic diseases in our country remains extremely topical and arguable problem that associated with many pending issues for doctors of various specialties, including those working as primary care specialists.Objective. The aim of the study is to develop major approaches and to prove scientifically the efficacy and safety of preventive vaccination for children with various chronic diseases.Methods. We have conducted comprehensive study of 100 children aged from 1 month to 17 years 11 months. Children were divided into 4 groups according to the specific disease. Vaccinal and infectious history was analyzed. The post-vaccination period was estimated due to the results of the questionnaire completed by parents. Vaccination immunogenicity was estimated based on the results of the level of specific antibodies to various controlled infections (measles, rubella, parotitis, hepatitis B, pertussis, haemophilus influenza type b).Results. Protective titers of antibodies against haemophilus influenza type b were revealed in 96.2% of all examined patients, tetanus and hepatitis B — in 95.2%, against pertussis — in 92.5%, rubella — in 91%, measles — in 87.5%, parotitis — in 71.9%, chickenpox — in 69% children a month after the completed vaccination. The postvaccinal period was characterized as favorable in most patients. Major changes in overall health status occurred after vaccination in 42% of children was the following: subfebrile fever, capriciousness, or fatigue. Local reactions have developed only in 15% of cases.Conclusion. The results of this study have demonstrated the preventive vaccination efficacy and safety in children with various chronic diseaseshttps://www.pedpharma.ru/jour/article/view/2098preventive vaccinationchildrenchronic diseasesvaccine efficacyvaccine safety |
| spellingShingle | Marina V. Fedoseenko Leyla S. Namazova-Baranova Elena A. Vishneva Svetlana V. Tolstova Arevaluis M. Selvyan Tatiana A. Kaliuzhnaia Firuza Ch. Shakhtakhtinskaya Margarita A. Soloshenko Tatiana E. Privalova Maria V. Fominyh Tatiana E. Zinovyeva Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results Педиатрическая фармакология preventive vaccination children chronic diseases vaccine efficacy vaccine safety |
| title | Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results |
| title_full | Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results |
| title_fullStr | Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results |
| title_full_unstemmed | Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results |
| title_short | Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results |
| title_sort | enhancement of preventive vaccination approaches for children with health problems prospective cohort study results |
| topic | preventive vaccination children chronic diseases vaccine efficacy vaccine safety |
| url | https://www.pedpharma.ru/jour/article/view/2098 |
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