Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone
The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their efficacy and safety in patients with hypertension, i...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2025-01-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/6190 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849690351679307776 |
|---|---|
| author | M. D. Smirnova T. V. Fofanova F. T. Ageyev |
| author_facet | M. D. Smirnova T. V. Fofanova F. T. Ageyev |
| author_sort | M. D. Smirnova |
| collection | DOAJ |
| description | The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their efficacy and safety in patients with hypertension, including those with comorbid pathology. Azilsartan medoxomil demonstrated greater efficacy with comparable safety in terms of lowering blood pressure, both office and ambulatory, compared to candesartan, valsartan, olmesartan. Chlorthalidone showed greater hypotensive efficacy compared to hydrochlorothiazide and proved its protective effect in cardiovascular risk reduction. The combination of azilsartan medoxomil/chlorthalidone, in turn, has proven its safety and greater hypotensive efficacy compared to both the combination of olmesartan medoxomil/hydrochlorothiazide and azilsartan medoxomil/hydrochlorothiazide. |
| format | Article |
| id | doaj-art-78d2b91b69db4823ab377c79bf8bcaea |
| institution | DOAJ |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2025-01-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-78d2b91b69db4823ab377c79bf8bcaea2025-08-20T03:21:19Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202025-01-01291210.15829/1560-4071-2024-61904296Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidoneM. D. Smirnova0T. V. Fofanova1F. T. Ageyev2Chazov National Medical Research Center for CardiologyChazov National Medical Research Center for CardiologyChazov National Medical Research Center for CardiologyThe article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their efficacy and safety in patients with hypertension, including those with comorbid pathology. Azilsartan medoxomil demonstrated greater efficacy with comparable safety in terms of lowering blood pressure, both office and ambulatory, compared to candesartan, valsartan, olmesartan. Chlorthalidone showed greater hypotensive efficacy compared to hydrochlorothiazide and proved its protective effect in cardiovascular risk reduction. The combination of azilsartan medoxomil/chlorthalidone, in turn, has proven its safety and greater hypotensive efficacy compared to both the combination of olmesartan medoxomil/hydrochlorothiazide and azilsartan medoxomil/hydrochlorothiazide.https://russjcardiol.elpub.ru/jour/article/view/6190antihypertensive therapyazilsartan medoxomilchlorthalidone |
| spellingShingle | M. D. Smirnova T. V. Fofanova F. T. Ageyev Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone Российский кардиологический журнал antihypertensive therapy azilsartan medoxomil chlorthalidone |
| title | Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone |
| title_full | Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone |
| title_fullStr | Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone |
| title_full_unstemmed | Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone |
| title_short | Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone |
| title_sort | looking for an optimal antihypertensive combination focus on azilsartan medoxomil chlorthalidone |
| topic | antihypertensive therapy azilsartan medoxomil chlorthalidone |
| url | https://russjcardiol.elpub.ru/jour/article/view/6190 |
| work_keys_str_mv | AT mdsmirnova lookingforanoptimalantihypertensivecombinationfocusonazilsartanmedoxomilchlorthalidone AT tvfofanova lookingforanoptimalantihypertensivecombinationfocusonazilsartanmedoxomilchlorthalidone AT ftageyev lookingforanoptimalantihypertensivecombinationfocusonazilsartanmedoxomilchlorthalidone |