Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies.

Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies.

Melanoma, a potentially lethal skin cancer, is widely thought to be immunogenic in nature. While there has been much focus on T cell-mediated immune responses, limited knowledge exists on the role of mature B cells. We describe an approach, including a cell-based ELISA, to evaluate mature IgG antibo...

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Main Authors: Amy E Gilbert, Panagiotis Karagiannis, Tihomir Dodev, Alexander Koers, Katie Lacy, Debra H Josephs, Pooja Takhar, Jenny L C Geh, Ciaran Healy, Mark Harries, Katharine M Acland, Sarah M Rudman, Rebecca L Beavil, Philip J Blower, Andrew J Beavil, Hannah J Gould, James Spicer, Frank O Nestle, Sophia N Karagiannis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019330&type=printable
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