Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital
Aim: to identify the prevalence of laboratoric ASA resistance using platelet function tests in patients with ischemic stroke at Cipto Mangunkusumo Hospital and its associated factors. Methods: this study was a cross-sectional study involving 50 patients with ischemic stroke who only received ASA tr...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2015-04-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | https://mail.actamedindones.org/index.php/ijim/article/view/43 |
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| author | M. Kurniawan Salim Harris Deddy Hermawan Joedo Prihartono |
| author_facet | M. Kurniawan Salim Harris Deddy Hermawan Joedo Prihartono |
| author_sort | M. Kurniawan |
| collection | DOAJ |
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Aim: to identify the prevalence of laboratoric ASA resistance using platelet function tests in patients with ischemic stroke at Cipto Mangunkusumo Hospital and its associated factors. Methods: this study was a cross-sectional study involving 50 patients with ischemic stroke who only received ASA treatment. Evaluation of resistance to ASA was performed using Verifynow® platelet function test. ASA resistance was defined as ASA reaction unit (ARU) ≥550. Results: there were 7 patients with ASA resistance. The mean age of subjects in ASA resistance group was 51.3±9.2 years; while in ASA responsive group was 57.8±9.7 years. In ASA resistance group, there were 85.7% male patients, 57.1% active smoker and 100% subjects with hypertension. Conclusion: the prevalence of laboratoric ASA resistance in patients with ischemic stroke evaluated using platelet function test at Cipto Mangunkusumo Hospital is 14%. The prevalence is more likely to occur in male patients who were active smoker, at younger age and with comorbidity of hypertension.
Key words: ischemic stroke, ASA resistance, platelet function test.
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| format | Article |
| id | doaj-art-78bedbb6f7c640c58866594a7ec91ec6 |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-78bedbb6f7c640c58866594a7ec91ec62025-08-20T02:48:17ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322015-04-01472Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo HospitalM. Kurniawan0Salim Harris1Deddy Hermawan2Joedo Prihartono3Department of Neurology, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaDepartment of Neurology, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaDepartment of Neurology, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaDepartment of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia. Aim: to identify the prevalence of laboratoric ASA resistance using platelet function tests in patients with ischemic stroke at Cipto Mangunkusumo Hospital and its associated factors. Methods: this study was a cross-sectional study involving 50 patients with ischemic stroke who only received ASA treatment. Evaluation of resistance to ASA was performed using Verifynow® platelet function test. ASA resistance was defined as ASA reaction unit (ARU) ≥550. Results: there were 7 patients with ASA resistance. The mean age of subjects in ASA resistance group was 51.3±9.2 years; while in ASA responsive group was 57.8±9.7 years. In ASA resistance group, there were 85.7% male patients, 57.1% active smoker and 100% subjects with hypertension. Conclusion: the prevalence of laboratoric ASA resistance in patients with ischemic stroke evaluated using platelet function test at Cipto Mangunkusumo Hospital is 14%. The prevalence is more likely to occur in male patients who were active smoker, at younger age and with comorbidity of hypertension. Key words: ischemic stroke, ASA resistance, platelet function test. https://mail.actamedindones.org/index.php/ijim/article/view/43 |
| spellingShingle | M. Kurniawan Salim Harris Deddy Hermawan Joedo Prihartono Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital Acta Medica Indonesiana |
| title | Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital |
| title_full | Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital |
| title_fullStr | Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital |
| title_full_unstemmed | Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital |
| title_short | Evaluating Resistance to Acetyl Salicylic Acid Using Platelet Function Test in Patients with Ischemic Stroke at Cipto Mangunkusumo Hospital |
| title_sort | evaluating resistance to acetyl salicylic acid using platelet function test in patients with ischemic stroke at cipto mangunkusumo hospital |
| url | https://mail.actamedindones.org/index.php/ijim/article/view/43 |
| work_keys_str_mv | AT mkurniawan evaluatingresistancetoacetylsalicylicacidusingplateletfunctiontestinpatientswithischemicstrokeatciptomangunkusumohospital AT salimharris evaluatingresistancetoacetylsalicylicacidusingplateletfunctiontestinpatientswithischemicstrokeatciptomangunkusumohospital AT deddyhermawan evaluatingresistancetoacetylsalicylicacidusingplateletfunctiontestinpatientswithischemicstrokeatciptomangunkusumohospital AT joedoprihartono evaluatingresistancetoacetylsalicylicacidusingplateletfunctiontestinpatientswithischemicstrokeatciptomangunkusumohospital |