Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis

The purpose of this investigation is to study antioxidant activity of sterically hindered phenol — thiophane in rats with toxical hepatitis. Increase of diene and triene conjugates as well as fluorescent products in hepar tissue was revealed. Course intragastric administration of thiophane decreased...

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Main Authors: V. I. Smoliyakova, M. B. Plotnikov, G. A. Chernyshyova, I. S. Ivanov, A. Ye. Prosenko, N. V. Kandalintseva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2010-10-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1667
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author V. I. Smoliyakova
M. B. Plotnikov
G. A. Chernyshyova
I. S. Ivanov
A. Ye. Prosenko
N. V. Kandalintseva
author_facet V. I. Smoliyakova
M. B. Plotnikov
G. A. Chernyshyova
I. S. Ivanov
A. Ye. Prosenko
N. V. Kandalintseva
author_sort V. I. Smoliyakova
collection DOAJ
description The purpose of this investigation is to study antioxidant activity of sterically hindered phenol — thiophane in rats with toxical hepatitis. Increase of diene and triene conjugates as well as fluorescent products in hepar tissue was revealed. Course intragastric administration of thiophane decreased significantly the content of lipid peroxidation products (diene and triene conjugates, fluorescent products) and held over the α-tocopherol content in hepar tissue.
format Article
id doaj-art-78bb7097cfb340debf5d63a4ed972189
institution DOAJ
issn 1682-0363
1819-3684
language English
publishDate 2010-10-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-78bb7097cfb340debf5d63a4ed9721892025-08-20T03:02:22ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842010-10-01959810110.20538/1682-0363-2010-5-98-1011169Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitisV. I. Smoliyakova0M. B. Plotnikov1G. A. Chernyshyova2I. S. Ivanov3A. Ye. Prosenko4N. V. Kandalintseva5НИИ фармакологии СО РАМННИИ фармакологии СО РАМННИИ фармакологии СО РАМННИИ фармакологии СО РАМННовосибирский государственный педагогический университетНовосибирский государственный педагогический университетThe purpose of this investigation is to study antioxidant activity of sterically hindered phenol — thiophane in rats with toxical hepatitis. Increase of diene and triene conjugates as well as fluorescent products in hepar tissue was revealed. Course intragastric administration of thiophane decreased significantly the content of lipid peroxidation products (diene and triene conjugates, fluorescent products) and held over the α-tocopherol content in hepar tissue.https://bulletin.ssmu.ru/jour/article/view/1667thiophanelipid peroxidationhepatoprotectortoxical hepatitis
spellingShingle V. I. Smoliyakova
M. B. Plotnikov
G. A. Chernyshyova
I. S. Ivanov
A. Ye. Prosenko
N. V. Kandalintseva
Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
Бюллетень сибирской медицины
thiophane
lipid peroxidation
hepatoprotector
toxical hepatitis
title Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
title_full Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
title_fullStr Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
title_full_unstemmed Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
title_short Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
title_sort antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane induced hepatitis
topic thiophane
lipid peroxidation
hepatoprotector
toxical hepatitis
url https://bulletin.ssmu.ru/jour/article/view/1667
work_keys_str_mv AT vismoliyakova antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis
AT mbplotnikov antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis
AT gachernyshyova antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis
AT isivanov antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis
AT ayeprosenko antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis
AT nvkandalintseva antioxidantactivityofthiophaneinratswithofexperimentaltetrachlorolmethaneinducedhepatitis