Drug-induced liver injuries (Part 1)
The aim of review. To present modern concepts on mechanisms of drug-induced liver injury (DILI), to give their classification, to present approaches to disease diagnostics.Original positions. DILI can progress under the mask of all known acute and chronic liver diseases. Pharmaceuticals act as one o...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2012-06-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1298 |
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| _version_ | 1823860206376845312 |
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| author | S. F. Galimova |
| author_facet | S. F. Galimova |
| author_sort | S. F. Galimova |
| collection | DOAJ |
| description | The aim of review. To present modern concepts on mechanisms of drug-induced liver injury (DILI), to give their classification, to present approaches to disease diagnostics.Original positions. DILI can progress under the mask of all known acute and chronic liver diseases. Pharmaceuticals act as one of the leading causes of development of fulminant liver failure in many countries of the world. Early diagnostics and well-timed cancellation of the drug causing liver damage, allow to prevent disease progression. Careful collection of medicinal past history, ruling out of other possible causes of liver injury and application of diagnostic scales (CIOMS/ RUCAM) lays in a basis of DILI diagnostics.Conclusion. Drug-induced lesions occupies significant place in major spectrum of liver diseases, welltimed diagnostics of these lesions enables to exclude intake of the respective agents. |
| format | Article |
| id | doaj-art-78ba9c1ba7404ef6b9147286d29515a0 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2012-06-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-78ba9c1ba7404ef6b9147286d29515a02025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732012-06-012233848870Drug-induced liver injuries (Part 1)S. F. Galimova0State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Health and Social Development of RussiaThe aim of review. To present modern concepts on mechanisms of drug-induced liver injury (DILI), to give their classification, to present approaches to disease diagnostics.Original positions. DILI can progress under the mask of all known acute and chronic liver diseases. Pharmaceuticals act as one of the leading causes of development of fulminant liver failure in many countries of the world. Early diagnostics and well-timed cancellation of the drug causing liver damage, allow to prevent disease progression. Careful collection of medicinal past history, ruling out of other possible causes of liver injury and application of diagnostic scales (CIOMS/ RUCAM) lays in a basis of DILI diagnostics.Conclusion. Drug-induced lesions occupies significant place in major spectrum of liver diseases, welltimed diagnostics of these lesions enables to exclude intake of the respective agents.https://www.gastro-j.ru/jour/article/view/1298drug-induced liver injuriesdiagnosticstreatment |
| spellingShingle | S. F. Galimova Drug-induced liver injuries (Part 1) Российский журнал гастроэнтерологии, гепатологии, колопроктологии drug-induced liver injuries diagnostics treatment |
| title | Drug-induced liver injuries (Part 1) |
| title_full | Drug-induced liver injuries (Part 1) |
| title_fullStr | Drug-induced liver injuries (Part 1) |
| title_full_unstemmed | Drug-induced liver injuries (Part 1) |
| title_short | Drug-induced liver injuries (Part 1) |
| title_sort | drug induced liver injuries part 1 |
| topic | drug-induced liver injuries diagnostics treatment |
| url | https://www.gastro-j.ru/jour/article/view/1298 |
| work_keys_str_mv | AT sfgalimova druginducedliverinjuriespart1 |