A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization

Considering the importance of organic functionalization of MOFs, we here report a simple, tunable and efficient one-step post-modification procedure for introducing amino and carboxylic groups into the mesoporous metal–organic framework Al- and Cr-MIL-101-NH<sub>2</sub> based on its reac...

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Main Authors: Alain Vigroux, Christian Lherbet, Isabelle Fabing, Marie-Claire Barthélémy, Christophe Laurent, Pascal Hoffmann
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Chemistry
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Online Access:https://www.mdpi.com/2624-8549/7/2/48
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author Alain Vigroux
Christian Lherbet
Isabelle Fabing
Marie-Claire Barthélémy
Christophe Laurent
Pascal Hoffmann
author_facet Alain Vigroux
Christian Lherbet
Isabelle Fabing
Marie-Claire Barthélémy
Christophe Laurent
Pascal Hoffmann
author_sort Alain Vigroux
collection DOAJ
description Considering the importance of organic functionalization of MOFs, we here report a simple, tunable and efficient one-step post-modification procedure for introducing amino and carboxylic groups into the mesoporous metal–organic framework Al- and Cr-MIL-101-NH<sub>2</sub> based on its reaction with alkyl bromides. This procedure allows also access to polyfunctionalized MIL-101 decorated with both carboxylic and primary amino groups. Other chemical functions, such as alcohols and alkynes, were also successfully introduced by this method.
format Article
id doaj-art-78b2c44bfde449ac84ec9e3ef5159049
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issn 2624-8549
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publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Chemistry
spelling doaj-art-78b2c44bfde449ac84ec9e3ef51590492025-08-20T03:14:17ZengMDPI AGChemistry2624-85492025-03-01724810.3390/chemistry7020048A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> FunctionalizationAlain Vigroux0Christian Lherbet1Isabelle Fabing2Marie-Claire Barthélémy3Christophe Laurent4Pascal Hoffmann5Laboratoire de Synthèse et Physico-Chimie de Molécules d’Interêt Biologique LSPCMIB, Université de Toulouse, UMR CNRS UT 5068, 118 Route de Narbonne, 31062 Toulouse, FranceLaboratoire de Synthèse et Physico-Chimie de Molécules d’Interêt Biologique LSPCMIB, Université de Toulouse, UMR CNRS UT 5068, 118 Route de Narbonne, 31062 Toulouse, FranceLaboratoire de Synthèse et Physico-Chimie de Molécules d’Interêt Biologique LSPCMIB, Université de Toulouse, UMR CNRS UT 5068, 118 Route de Narbonne, 31062 Toulouse, FranceCentre Interuniversitaire de Recherche et d’Ingénierie des Matériaux CIRIMAT, Université de Toulouse, UMR CNRS INP UT 5085, 118 Route de Narbonne, 31062 Toulouse, FranceCentre Interuniversitaire de Recherche et d’Ingénierie des Matériaux CIRIMAT, Université de Toulouse, UMR CNRS INP UT 5085, 118 Route de Narbonne, 31062 Toulouse, FranceLaboratoire de Synthèse et Physico-Chimie de Molécules d’Interêt Biologique LSPCMIB, Université de Toulouse, UMR CNRS UT 5068, 118 Route de Narbonne, 31062 Toulouse, FranceConsidering the importance of organic functionalization of MOFs, we here report a simple, tunable and efficient one-step post-modification procedure for introducing amino and carboxylic groups into the mesoporous metal–organic framework Al- and Cr-MIL-101-NH<sub>2</sub> based on its reaction with alkyl bromides. This procedure allows also access to polyfunctionalized MIL-101 decorated with both carboxylic and primary amino groups. Other chemical functions, such as alcohols and alkynes, were also successfully introduced by this method.https://www.mdpi.com/2624-8549/7/2/48metal–organic frameworkspost-synthetic modificationPSM(Al)MIL101-NH<sub>2</sub>(Cr)MIL101-NH<sub>2</sub>alkylation
spellingShingle Alain Vigroux
Christian Lherbet
Isabelle Fabing
Marie-Claire Barthélémy
Christophe Laurent
Pascal Hoffmann
A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
Chemistry
metal–organic frameworks
post-synthetic modification
PSM
(Al)MIL101-NH<sub>2</sub>
(Cr)MIL101-NH<sub>2</sub>
alkylation
title A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
title_full A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
title_fullStr A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
title_full_unstemmed A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
title_short A Post-Synthetic Modification Approach to Expand MIL-101-NH<sub>2</sub> Functionalization
title_sort post synthetic modification approach to expand mil 101 nh sub 2 sub functionalization
topic metal–organic frameworks
post-synthetic modification
PSM
(Al)MIL101-NH<sub>2</sub>
(Cr)MIL101-NH<sub>2</sub>
alkylation
url https://www.mdpi.com/2624-8549/7/2/48
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