The Gut Microbiota and Respiratory Diseases: New Evidence
Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with the gut being the most densely and extensively colonized organ. The microbiome plays an essential role in immune s...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2020/2340670 |
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| author | Li Chunxi Liu Haiyue Lin Yanxia Pan Jianbing Su Jin |
| author_facet | Li Chunxi Liu Haiyue Lin Yanxia Pan Jianbing Su Jin |
| author_sort | Li Chunxi |
| collection | DOAJ |
| description | Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with the gut being the most densely and extensively colonized organ. The microbiome plays an essential role in immune system development and tissue homeostasis. Gut microbiota dysbiosis not only modulates the immune responses of the gastrointestinal (GI) tract but also impacts the immunity of distal organs, such as the lung, further affecting lung health and respiratory diseases. Here, we review the recent evidence of the correlations and underlying mechanisms of the relationship between the gut microbiota and common respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), lung cancer, and respiratory infection, and probiotic development as a therapeutic intervention for these diseases. |
| format | Article |
| id | doaj-art-78b1477cd60e414bb4a164f1d9b1d306 |
| institution | OA Journals |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-78b1477cd60e414bb4a164f1d9b1d3062025-08-20T02:07:28ZengWileyJournal of Immunology Research2314-88612314-71562020-01-01202010.1155/2020/23406702340670The Gut Microbiota and Respiratory Diseases: New EvidenceLi Chunxi0Liu Haiyue1Lin Yanxia2Pan Jianbing3Su Jin4Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangdong Guangzhou 510515, ChinaDepartment of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangdong Guangzhou 510282, ChinaDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangdong Guangzhou 510515, ChinaDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangdong Guangzhou 510515, ChinaDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangdong Guangzhou 510515, ChinaHuman body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with the gut being the most densely and extensively colonized organ. The microbiome plays an essential role in immune system development and tissue homeostasis. Gut microbiota dysbiosis not only modulates the immune responses of the gastrointestinal (GI) tract but also impacts the immunity of distal organs, such as the lung, further affecting lung health and respiratory diseases. Here, we review the recent evidence of the correlations and underlying mechanisms of the relationship between the gut microbiota and common respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), lung cancer, and respiratory infection, and probiotic development as a therapeutic intervention for these diseases.http://dx.doi.org/10.1155/2020/2340670 |
| spellingShingle | Li Chunxi Liu Haiyue Lin Yanxia Pan Jianbing Su Jin The Gut Microbiota and Respiratory Diseases: New Evidence Journal of Immunology Research |
| title | The Gut Microbiota and Respiratory Diseases: New Evidence |
| title_full | The Gut Microbiota and Respiratory Diseases: New Evidence |
| title_fullStr | The Gut Microbiota and Respiratory Diseases: New Evidence |
| title_full_unstemmed | The Gut Microbiota and Respiratory Diseases: New Evidence |
| title_short | The Gut Microbiota and Respiratory Diseases: New Evidence |
| title_sort | gut microbiota and respiratory diseases new evidence |
| url | http://dx.doi.org/10.1155/2020/2340670 |
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