Balancing ethics and statistics: machine learning facilitates highly accurate classification of mice according to their trait anxiety with reduced sample sizes

Abstract Understanding how individual differences influence vulnerability to disease and responses to pharmacological treatments represents one of the main challenges in behavioral neuroscience. Nevertheless, inter-individual variability and sex-specific patterns have been long disregarded in precli...

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Bibliographic Details
Main Authors: Johannes Miedema, Beat Lutz, Susanne Gerber, Irina Kovlyagina, Hristo Todorov
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03546-6
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