Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants
Objective: The study aimed to compare the risk factors, treatment strategies, and early outcomes of symptomatic neonatal pneumothorax (NP) between preterm and term newborns. Materials and Methods: This retrospective cross-sectional study was conducted in a neonatal intensive care unit between 201...
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| Format: | Article |
| Language: | English |
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AVES Yayincilik
2024-01-01
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| Series: | Turkish Archives of Pediatrics |
| Online Access: | https://turkarchpediatr.org/en/differences-in-possible-risk-factors-treatment-strategies-and-outcomes-of-neonatal-pneumothorax-in-preterm-and-term-infants-131599 |
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| author | Ümit Ayşe Tandırcıoğlu Ümran Koral Nilüfer Güzoğlu Serdar Alan Didem Aliefendioğlu |
| author_facet | Ümit Ayşe Tandırcıoğlu Ümran Koral Nilüfer Güzoğlu Serdar Alan Didem Aliefendioğlu |
| author_sort | Ümit Ayşe Tandırcıoğlu |
| collection | DOAJ |
| description | Objective: The study aimed to compare the risk factors, treatment strategies, and early outcomes of symptomatic neonatal pneumothorax (NP) between preterm and term newborns.
Materials and Methods: This retrospective cross-sectional study was conducted in a neonatal intensive care unit between 2015 and 2022, consisting of hospitalized neonates with symptomatic NP. The cases were divided into three groups according to their gestational ages: <340/7 (group 1), 340/7-366/7 (group 2), and ≥370/7 weeks (group 3). Risk factors, treatment strategies, and mortality rates of the study groups were compared using Kruskal–Wallis analysis.
Results: Fifty-nine infants with a diagnosis of symptomatic NP were included in the study. The number of participants was as follows: 25 (42.3%) in group 1, 18 (30.5%) in group 2, and 16 (27.1%) in group 3. The need of delivery room (DR) resuscitation was significantly higher in group 1 (40%, P = .003). The surfactant administration rate was significantly higher in group 1 when compared to group 2 and group 3 (68% vs. 22% and 19%, respectively), P < .001. Similarly, the invasive mechanical ventilation percentage was significantly higher in group 1 than group 2 and group 3, P = .014. However, compared to group 3 (63%), the percentage of chest drain insertion (CDI) need was significantly higher in group 1 (96%) and group 2 (89%) (P = .014).
Conclusion: Exposure to DR resuscitation and the need for surfactant are the most common risk factors for NP in preterm infants. Although oxygen and/or needle aspiration treatments are less invasive in symptomatic NP, the improvement rate without CDI is very low in preterm infants born before 34 weeks of gestational age. |
| format | Article |
| id | doaj-art-789ab59835124e41849ae246f4093ee3 |
| institution | Kabale University |
| issn | 2757-6256 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | AVES Yayincilik |
| record_format | Article |
| series | Turkish Archives of Pediatrics |
| spelling | doaj-art-789ab59835124e41849ae246f4093ee32024-11-26T13:16:48ZengAVES YayincilikTurkish Archives of Pediatrics2757-62562024-01-01591879210.5152/TurkArchPediatr.2024.23124Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term InfantsÜmit Ayşe Tandırcıoğlu0 Ümran Koral1Nilüfer Güzoğlu2Serdar Alan3Didem Aliefendioğlu4Division of Neonatology, Department of Pediatrics, Kırıkkale University Faculty of Medicine, Kırıkkale, TurkeyDepartment of Pediatrics, Kırıkkale University Faculty of Medicine, Kırıkkale, TurkeyDepartment of Pediatrics, Eastern Mediterranean University Faculty of Medicine, Famagusta, Turkish Republic of Northern CyprusDivision of Neonatology, Department of Pediatrics, Kırıkkale University Faculty of Medicine, Kırıkkale, TurkeyDivision of Neonatology, Department of Pediatrics, Güven Hospital, Ankara, TurkeyObjective: The study aimed to compare the risk factors, treatment strategies, and early outcomes of symptomatic neonatal pneumothorax (NP) between preterm and term newborns. Materials and Methods: This retrospective cross-sectional study was conducted in a neonatal intensive care unit between 2015 and 2022, consisting of hospitalized neonates with symptomatic NP. The cases were divided into three groups according to their gestational ages: <340/7 (group 1), 340/7-366/7 (group 2), and ≥370/7 weeks (group 3). Risk factors, treatment strategies, and mortality rates of the study groups were compared using Kruskal–Wallis analysis. Results: Fifty-nine infants with a diagnosis of symptomatic NP were included in the study. The number of participants was as follows: 25 (42.3%) in group 1, 18 (30.5%) in group 2, and 16 (27.1%) in group 3. The need of delivery room (DR) resuscitation was significantly higher in group 1 (40%, P = .003). The surfactant administration rate was significantly higher in group 1 when compared to group 2 and group 3 (68% vs. 22% and 19%, respectively), P < .001. Similarly, the invasive mechanical ventilation percentage was significantly higher in group 1 than group 2 and group 3, P = .014. However, compared to group 3 (63%), the percentage of chest drain insertion (CDI) need was significantly higher in group 1 (96%) and group 2 (89%) (P = .014). Conclusion: Exposure to DR resuscitation and the need for surfactant are the most common risk factors for NP in preterm infants. Although oxygen and/or needle aspiration treatments are less invasive in symptomatic NP, the improvement rate without CDI is very low in preterm infants born before 34 weeks of gestational age.https://turkarchpediatr.org/en/differences-in-possible-risk-factors-treatment-strategies-and-outcomes-of-neonatal-pneumothorax-in-preterm-and-term-infants-131599 |
| spellingShingle | Ümit Ayşe Tandırcıoğlu Ümran Koral Nilüfer Güzoğlu Serdar Alan Didem Aliefendioğlu Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants Turkish Archives of Pediatrics |
| title | Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants |
| title_full | Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants |
| title_fullStr | Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants |
| title_full_unstemmed | Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants |
| title_short | Differences in Possible Risk Factors, Treatment Strategies, and Outcomes of Neonatal Pneumothorax in Preterm and Term Infants |
| title_sort | differences in possible risk factors treatment strategies and outcomes of neonatal pneumothorax in preterm and term infants |
| url | https://turkarchpediatr.org/en/differences-in-possible-risk-factors-treatment-strategies-and-outcomes-of-neonatal-pneumothorax-in-preterm-and-term-infants-131599 |
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