F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1.

F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1.

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Protein ubiquitination is usually coupled with proteasomal degradation and is crucial in regulating protein quality. The E3 ubiquitin-protein ligase SCF (Skp1-Cullin-F-box) complex directly recognizes the target substrate via interaction between the F-box protein and the substrate. F-box protein is...

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Bibliographic Details
Main Authors: Zhongjiao Liu, Kexuan Ma, Panpan Zhang, Siqi Zhang, Xin Song, Yuqi Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011539
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