Genomic evolution and dissemination of non-conjugative virulence plasmid of ST65 carbapenem-resistant and hypervirulent Klebsiella pneumoniae strains in a Chinese hospital

Genomic evolution and dissemination of non-conjugative virulence plasmid of ST65 carbapenem-resistant and hypervirulent Klebsiella pneumoniae strains in a Chinese hospital

BackgroundThe global rise in infections caused by hypervirulent and carbapenem-resistant K. pneumoniae (CR-hvKp) represents a growing public health threat. This study investigates ST65 CR-hvKp strains, with a focus on their genomic attributes and the mechanisms underlying the transmission of non-con...

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Bibliographic Details
Main Authors: Dongxing Tian, Mingqi Zhao, Lihua Liu, Shuhua Lu, Haixin Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Klebsiella pneumoniae
hypervirulence
carbapenem resistance
plasmid transmission
ST65
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1548300/full
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