Behavioral signature of trihexyphenidyl in the TOR1A (DYT1) knockin mouse model of dystonia
Dystonia is a neurological disorder characterized by involuntary repetitive movements and abnormal postures. Animal models have played a pivotal role in studying the pathophysiology of dystonia. However, many genetic models, e.g., the Tor1a+/ΔE (DYT1) mouse, lack an overt motor phenotype, despite si...
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| Main Authors: | Ahmad Abdal Qader, Yuping Donsante, Jeffrey E. Markowitz, H. A. Jinnah, Chethan Pandarinath, Ellen J. Hess |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Dystonia |
| Subjects: | |
| Online Access: | https://www.frontierspartnerships.org/articles/10.3389/dyst.2025.15034/full |
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