A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results
Purpose. To compare the corneal endothelial cell loss after phacoemulsification, alone or combined with microinvasive glaucoma surgery (MIGS), in nonglaucomatous versus primary open angle glaucoma (POAG) eyes affected by age-related cataract. Methods. 62 eyes of 62 patients were divided into group 1...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/769289 |
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| author | Antonio M. Fea Giulia Consolandi Giulia Pignata Paola Maria Loredana Cannizzo Carlo Lavia Filippo Billia Teresa Rolle Federico M. Grignolo |
| author_facet | Antonio M. Fea Giulia Consolandi Giulia Pignata Paola Maria Loredana Cannizzo Carlo Lavia Filippo Billia Teresa Rolle Federico M. Grignolo |
| author_sort | Antonio M. Fea |
| collection | DOAJ |
| description | Purpose. To compare the corneal endothelial cell loss after phacoemulsification, alone or combined with microinvasive glaucoma surgery (MIGS), in nonglaucomatous versus primary open angle glaucoma (POAG) eyes affected by age-related cataract. Methods. 62 eyes of 62 patients were divided into group 1 (n=25, affected by age-related cataract) and group 2 (n=37, affected by age-related cataract and POAG). All patients underwent cataract surgery. Group 2 was divided into subgroups A (n=19, cataract surgery alone) and B (n=18, cataract surgery and MIGS). Prior to and 6 months after surgery the patients’ endothelium was studied. Main outcomes were CD (cell density), SD (standard deviation), CV (coefficient of variation), and 6A (hexagonality coefficient) variations after surgeries. Results. There were no significant differences among the groups concerning preoperative endothelial parameters. The differences in CD before and after surgery were significant in all groups: 9.1% in group 1, 17.24% in group 2A, and 11.71% in group 2B. All endothelial parameters did not significantly change after surgery. Conclusions. Phacoemulsification determined a loss of endothelial cells in all groups. After surgery the change in endothelial parameters after MIGS was comparable to the ones of patients who underwent cataract surgery alone. |
| format | Article |
| id | doaj-art-786f03d0b7d34e9e8ff866d7bfea785e |
| institution | OA Journals |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-786f03d0b7d34e9e8ff866d7bfea785e2025-08-20T02:07:31ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/769289769289A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month ResultsAntonio M. Fea0Giulia Consolandi1Giulia Pignata2Paola Maria Loredana Cannizzo3Carlo Lavia4Filippo Billia5Teresa Rolle6Federico M. Grignolo7Department of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Turin, 10122 Turin, ItalyPurpose. To compare the corneal endothelial cell loss after phacoemulsification, alone or combined with microinvasive glaucoma surgery (MIGS), in nonglaucomatous versus primary open angle glaucoma (POAG) eyes affected by age-related cataract. Methods. 62 eyes of 62 patients were divided into group 1 (n=25, affected by age-related cataract) and group 2 (n=37, affected by age-related cataract and POAG). All patients underwent cataract surgery. Group 2 was divided into subgroups A (n=19, cataract surgery alone) and B (n=18, cataract surgery and MIGS). Prior to and 6 months after surgery the patients’ endothelium was studied. Main outcomes were CD (cell density), SD (standard deviation), CV (coefficient of variation), and 6A (hexagonality coefficient) variations after surgeries. Results. There were no significant differences among the groups concerning preoperative endothelial parameters. The differences in CD before and after surgery were significant in all groups: 9.1% in group 1, 17.24% in group 2A, and 11.71% in group 2B. All endothelial parameters did not significantly change after surgery. Conclusions. Phacoemulsification determined a loss of endothelial cells in all groups. After surgery the change in endothelial parameters after MIGS was comparable to the ones of patients who underwent cataract surgery alone.http://dx.doi.org/10.1155/2015/769289 |
| spellingShingle | Antonio M. Fea Giulia Consolandi Giulia Pignata Paola Maria Loredana Cannizzo Carlo Lavia Filippo Billia Teresa Rolle Federico M. Grignolo A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results Journal of Ophthalmology |
| title | A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results |
| title_full | A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results |
| title_fullStr | A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results |
| title_full_unstemmed | A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results |
| title_short | A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results |
| title_sort | comparison of endothelial cell loss in combined cataract and migs hydrus procedure to phacoemulsification alone 6 month results |
| url | http://dx.doi.org/10.1155/2015/769289 |
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