Prophylactic use of recombinant ADAMTS-13 during pregnancy for congenital thrombotic thrombocytopenic purpura
Background: Congenital thrombotic thrombocytopenic purpura (cTTP) related to ADAMTS-13 deficiency is associated with a maternal risk of death of 10% and a risk of fetal loss greater than 50% without treatment. Key Clinical Question: Is prophylactic use of recombinant (r)ADAMTS-13 during pregnancy in...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Research and Practice in Thrombosis and Haemostasis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2475037925000111 |
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