Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea
Background. Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods. Patients with T2DM with OSA (n=33) and witho...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/4121794 |
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| author | Thomas Rehling Anne Margareta Banghøj Marie Hvelplund Kristiansen Lise Tarnow Stig Molsted |
| author_facet | Thomas Rehling Anne Margareta Banghøj Marie Hvelplund Kristiansen Lise Tarnow Stig Molsted |
| author_sort | Thomas Rehling |
| collection | DOAJ |
| description | Background. Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods. Patients with T2DM with OSA (n=33) and without OSA (n=28) were included. The maximum IMS was tested using the POWERbreathe KH2 device. Reference IMS values were data calculated using an algorithm based on general populations and adjusted for age and gender. Results. There was no difference in IMS between the OSA group (median (range) 77 (35–124) cmH2O) and the non-OSA group (84 (33–122) cmH2O) (p=0.97). The IMS values were reduced in the OSA group compared with the reference values (92.9 (62.3–100.0) cmH2O) (p=0.030), whereas the non-OSA group did not have reduced IMS. When the IMS values of all T2DM patients were compared with reference values, the IMS values were 79 (33–124) cmH2O and 93.8 (62.3–102.4) cmH2O, respectively (p=0.017). Conclusion. No difference in IMS between patients with T2DM with or without OSA was found. However, patients with T2DM and OSA had reduced IMS compared with age- and gender-matched references whereas the non-OSA group did not have reduced IMS. |
| format | Article |
| id | doaj-art-786738eb135145bea8db577325d38319 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-786738eb135145bea8db577325d383192025-02-03T05:45:25ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/41217944121794Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep ApnoeaThomas Rehling0Anne Margareta Banghøj1Marie Hvelplund Kristiansen2Lise Tarnow3Stig Molsted4University College (UCC) Department of Physiotherapy, Hillerød, DenmarkDepartment of Cardiology, Nephrology & Endocrinology, Nordsjællands Hospital, Hillerød, DenmarkDepartment of Cardiology, Nephrology & Endocrinology, Nordsjællands Hospital, Hillerød, DenmarkDepartment of Clinical Research, Nordsjællands Hospital, Hillerød, DenmarkDepartment of Cardiology, Nephrology & Endocrinology, Nordsjællands Hospital, Hillerød, DenmarkBackground. Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods. Patients with T2DM with OSA (n=33) and without OSA (n=28) were included. The maximum IMS was tested using the POWERbreathe KH2 device. Reference IMS values were data calculated using an algorithm based on general populations and adjusted for age and gender. Results. There was no difference in IMS between the OSA group (median (range) 77 (35–124) cmH2O) and the non-OSA group (84 (33–122) cmH2O) (p=0.97). The IMS values were reduced in the OSA group compared with the reference values (92.9 (62.3–100.0) cmH2O) (p=0.030), whereas the non-OSA group did not have reduced IMS. When the IMS values of all T2DM patients were compared with reference values, the IMS values were 79 (33–124) cmH2O and 93.8 (62.3–102.4) cmH2O, respectively (p=0.017). Conclusion. No difference in IMS between patients with T2DM with or without OSA was found. However, patients with T2DM and OSA had reduced IMS compared with age- and gender-matched references whereas the non-OSA group did not have reduced IMS.http://dx.doi.org/10.1155/2017/4121794 |
| spellingShingle | Thomas Rehling Anne Margareta Banghøj Marie Hvelplund Kristiansen Lise Tarnow Stig Molsted Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea Journal of Diabetes Research |
| title | Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea |
| title_full | Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea |
| title_fullStr | Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea |
| title_full_unstemmed | Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea |
| title_short | Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea |
| title_sort | reduced inspiratory muscle strength in patients with type 2 diabetes mellitus and obstructive sleep apnoea |
| url | http://dx.doi.org/10.1155/2017/4121794 |
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