Resistant Hypertension in Nondialysis Chronic Kidney Disease
Resistant hypertension (RH) is defined as blood pressure (BP) that remains above the target of less than 140/90 mmHg in the general population and 130/80 mmHg in people with diabetes mellitus or chronic kidney disease (CKD) in spite of the use of at least three full-dose antihypertensive drugs inclu...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2013/929183 |
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| author | Silvio Borrelli Luca De Nicola Giovanna Stanzione Giuseppe Conte Roberto Minutolo |
| author_facet | Silvio Borrelli Luca De Nicola Giovanna Stanzione Giuseppe Conte Roberto Minutolo |
| author_sort | Silvio Borrelli |
| collection | DOAJ |
| description | Resistant hypertension (RH) is defined as blood pressure (BP) that remains above the target of less than 140/90 mmHg in the general population and 130/80 mmHg in people with diabetes mellitus or chronic kidney disease (CKD) in spite of the use of at least three full-dose antihypertensive drugs including a diuretic or as BP that reaches the target by means of four or more drugs. In CKD, RH is a common condition due to a combination of factors including sodium retention, increased activity of the renin-angiotensin system, and enhanced activity of the sympathetic nervous system. Before defining the hypertensive patient as resistant it is mandatory to exclude the so-called “pseudoresistance.” This condition, which refers to the apparent failure to reach BP target in spite of an appropriate antihypertensive treatment, is mainly caused by white coat hypertension that is prevalent (30%) in CKD patients. Recently we have demonstrated that “true” RH represents an independent risk factor for renal and cardiovascular outcomes in CKD patients. |
| format | Article |
| id | doaj-art-7864868188fe418ab0c19525627f2b8b |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-7864868188fe418ab0c19525627f2b8b2025-02-03T00:59:28ZengWileyInternational Journal of Hypertension2090-03842090-03922013-01-01201310.1155/2013/929183929183Resistant Hypertension in Nondialysis Chronic Kidney DiseaseSilvio Borrelli0Luca De Nicola1Giovanna Stanzione2Giuseppe Conte3Roberto Minutolo4Division of Nephrology, Second University of Naples, 80125 Naples, ItalyDivision of Nephrology, Second University of Naples, 80125 Naples, ItalyDivision of Nephrology, Second University of Naples, 80125 Naples, ItalyDivision of Nephrology, Second University of Naples, 80125 Naples, ItalyDivision of Nephrology, Second University of Naples, 80125 Naples, ItalyResistant hypertension (RH) is defined as blood pressure (BP) that remains above the target of less than 140/90 mmHg in the general population and 130/80 mmHg in people with diabetes mellitus or chronic kidney disease (CKD) in spite of the use of at least three full-dose antihypertensive drugs including a diuretic or as BP that reaches the target by means of four or more drugs. In CKD, RH is a common condition due to a combination of factors including sodium retention, increased activity of the renin-angiotensin system, and enhanced activity of the sympathetic nervous system. Before defining the hypertensive patient as resistant it is mandatory to exclude the so-called “pseudoresistance.” This condition, which refers to the apparent failure to reach BP target in spite of an appropriate antihypertensive treatment, is mainly caused by white coat hypertension that is prevalent (30%) in CKD patients. Recently we have demonstrated that “true” RH represents an independent risk factor for renal and cardiovascular outcomes in CKD patients.http://dx.doi.org/10.1155/2013/929183 |
| spellingShingle | Silvio Borrelli Luca De Nicola Giovanna Stanzione Giuseppe Conte Roberto Minutolo Resistant Hypertension in Nondialysis Chronic Kidney Disease International Journal of Hypertension |
| title | Resistant Hypertension in Nondialysis Chronic Kidney Disease |
| title_full | Resistant Hypertension in Nondialysis Chronic Kidney Disease |
| title_fullStr | Resistant Hypertension in Nondialysis Chronic Kidney Disease |
| title_full_unstemmed | Resistant Hypertension in Nondialysis Chronic Kidney Disease |
| title_short | Resistant Hypertension in Nondialysis Chronic Kidney Disease |
| title_sort | resistant hypertension in nondialysis chronic kidney disease |
| url | http://dx.doi.org/10.1155/2013/929183 |
| work_keys_str_mv | AT silvioborrelli resistanthypertensioninnondialysischronickidneydisease AT lucadenicola resistanthypertensioninnondialysischronickidneydisease AT giovannastanzione resistanthypertensioninnondialysischronickidneydisease AT giuseppeconte resistanthypertensioninnondialysischronickidneydisease AT robertominutolo resistanthypertensioninnondialysischronickidneydisease |