Monoclonal Antibodies Against Vascular Endothelial Growth Factor A (VEGF-A) Reduce Synovitis, Bone Damage, and Osteogenesis in an SKG Mouse Model of Spondyloarthritis

Monoclonal Antibodies Against Vascular Endothelial Growth Factor A (VEGF-A) Reduce Synovitis, Bone Damage, and Osteogenesis in an SKG Mouse Model of Spondyloarthritis

Vascular endothelial growth factor-A (VEGF-A) plays a pivotal role in inflammatory rheumatic diseases, including spondyloarthritis (SpA). Recently, we have demonstrated that the expression of VEGF-A in human classical monocytes is positively associated with the number of swollen and painful joints i...

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Main Authors: Marcin Czepiel, Małgorzata Stec, Anna Gąsiorek, Anna Gałuszka, Kornelia Kłosińska, Joanna Kozieł, Jarosław Czyż, Jarosław Baran, Przemysław Błyszczuk, Maciej Siedlar, Mariusz Korkosz
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/jimr/8870895
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