Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan

Chemical cross-linking was developed to prepare starch and chitosan-based hydrogels. First, the precursor of starch was synthesized through the reaction of carboxymethylation with sodium monochloroacetate, and then chitosan was grafted by using methacrylic acid as cross-linker. In this research, sag...

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Main Authors: Titi Candra Sunarti, M. Irsan Febrian, Eka Ruriani, Indah Yuliasih
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2019/1542128
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author Titi Candra Sunarti
M. Irsan Febrian
Eka Ruriani
Indah Yuliasih
author_facet Titi Candra Sunarti
M. Irsan Febrian
Eka Ruriani
Indah Yuliasih
author_sort Titi Candra Sunarti
collection DOAJ
description Chemical cross-linking was developed to prepare starch and chitosan-based hydrogels. First, the precursor of starch was synthesized through the reaction of carboxymethylation with sodium monochloroacetate, and then chitosan was grafted by using methacrylic acid as cross-linker. In this research, sago and cassava starches were used and mixed with chitosan, and the effect of methacrylic acid concentration was investigated to determine the grafting parameters and hydrogel characteristics. Compared to native starch and carboxymethylated starch, hydrogels from both starches have high ability to swell and high capacity to absorb water and oil. The highest grafting yield, grafting efficiency, and monomer conversion were achieved by experiment using 0.550 g of methacrylic acid per g of CMS-chitosan mixture. These hydrogels have a good potency as biodegradable absorbents for pharmaceutical and industrial application.
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institution OA Journals
issn 1687-8787
1687-8795
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series International Journal of Biomaterials
spelling doaj-art-7842e92b41db4d989a83c0dc6a1416cf2025-08-20T02:07:30ZengWileyInternational Journal of Biomaterials1687-87871687-87952019-01-01201910.1155/2019/15421281542128Some Properties of Chemical Cross-Linking Biohydrogel from Starch and ChitosanTiti Candra Sunarti0M. Irsan Febrian1Eka Ruriani2Indah Yuliasih3Department of Agroindustrial Technology, Bogor Agricultural University, Kampus IPB Dramaga, PO Box 220, Bogor, 16680, IndonesiaDepartment of Agroindustrial Technology, Bogor Agricultural University, Kampus IPB Dramaga, PO Box 220, Bogor, 16680, IndonesiaDepartment of Agroindustrial Technology, Bogor Agricultural University, Kampus IPB Dramaga, PO Box 220, Bogor, 16680, IndonesiaDepartment of Agroindustrial Technology, Bogor Agricultural University, Kampus IPB Dramaga, PO Box 220, Bogor, 16680, IndonesiaChemical cross-linking was developed to prepare starch and chitosan-based hydrogels. First, the precursor of starch was synthesized through the reaction of carboxymethylation with sodium monochloroacetate, and then chitosan was grafted by using methacrylic acid as cross-linker. In this research, sago and cassava starches were used and mixed with chitosan, and the effect of methacrylic acid concentration was investigated to determine the grafting parameters and hydrogel characteristics. Compared to native starch and carboxymethylated starch, hydrogels from both starches have high ability to swell and high capacity to absorb water and oil. The highest grafting yield, grafting efficiency, and monomer conversion were achieved by experiment using 0.550 g of methacrylic acid per g of CMS-chitosan mixture. These hydrogels have a good potency as biodegradable absorbents for pharmaceutical and industrial application.http://dx.doi.org/10.1155/2019/1542128
spellingShingle Titi Candra Sunarti
M. Irsan Febrian
Eka Ruriani
Indah Yuliasih
Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
International Journal of Biomaterials
title Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
title_full Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
title_fullStr Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
title_full_unstemmed Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
title_short Some Properties of Chemical Cross-Linking Biohydrogel from Starch and Chitosan
title_sort some properties of chemical cross linking biohydrogel from starch and chitosan
url http://dx.doi.org/10.1155/2019/1542128
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