Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine
We present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective.
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| Format: | Article |
| Language: | English |
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Elsevier
2024-11-01
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| Series: | Journal of Allergy and Clinical Immunology: Global |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772829324001358 |
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| author | Amin Esmailian, BSC (Hons), MD Sara Laura Barnes, MBBS (Hons), MBA, FRACP, ADJAOP Marsus Pumar, BBiomedSc (Hons), BMBS, MPhil |
| author_facet | Amin Esmailian, BSC (Hons), MD Sara Laura Barnes, MBBS (Hons), MBA, FRACP, ADJAOP Marsus Pumar, BBiomedSc (Hons), BMBS, MPhil |
| author_sort | Amin Esmailian, BSC (Hons), MD |
| collection | DOAJ |
| description | We present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective. |
| format | Article |
| id | doaj-art-7841be3678d04649944467d19e618ef3 |
| institution | OA Journals |
| issn | 2772-8293 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Allergy and Clinical Immunology: Global |
| spelling | doaj-art-7841be3678d04649944467d19e618ef32025-08-20T02:14:50ZengElsevierJournal of Allergy and Clinical Immunology: Global2772-82932024-11-013410033910.1016/j.jacig.2024.100339Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccineAmin Esmailian, BSC (Hons), MD0Sara Laura Barnes, MBBS (Hons), MBA, FRACP, ADJAOP1Marsus Pumar, BBiomedSc (Hons), BMBS, MPhil2Faculty of Medicine, Monash University, Melbourne, Australia; Corresponding author: Amin Esmailian, BSC (Hons), MD, Faculty of Medicine, Monash University, 27 Rainforest walk, Clayton, Victoria, Australia. VIC 3168.Faculty of Medicine, Monash University, Melbourne, Australia; Monash Lung Sleep Allergy and Immunology, Clayton, Australia; Monash Health, Clayton, AustraliaMonash Health, Clayton, AustraliaWe present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective.http://www.sciencedirect.com/science/article/pii/S2772829324001358Secondary T-cell deficiencychronic spontaneous urticariaCOVID-19 vaccineomalizumabidiopathic total lymphopeniaautoimmune-induced lymphopenia |
| spellingShingle | Amin Esmailian, BSC (Hons), MD Sara Laura Barnes, MBBS (Hons), MBA, FRACP, ADJAOP Marsus Pumar, BBiomedSc (Hons), BMBS, MPhil Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine Journal of Allergy and Clinical Immunology: Global Secondary T-cell deficiency chronic spontaneous urticaria COVID-19 vaccine omalizumab idiopathic total lymphopenia autoimmune-induced lymphopenia |
| title | Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine |
| title_full | Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine |
| title_fullStr | Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine |
| title_full_unstemmed | Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine |
| title_short | Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine |
| title_sort | case report of secondary t cell deficiency following the astrazeneca covid 19 vaccine |
| topic | Secondary T-cell deficiency chronic spontaneous urticaria COVID-19 vaccine omalizumab idiopathic total lymphopenia autoimmune-induced lymphopenia |
| url | http://www.sciencedirect.com/science/article/pii/S2772829324001358 |
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