Predictor factors of uncontrolled diabetes
Abstract Objective The most significant challenge faced by individuals with diabetes is poor blood sugar control. The objective of this review is to identify the most crucial predictors of poor glycemic control among patients with diabetes. Materials This review employed a comprehensive approach, ut...
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| Format: | Article |
| Language: | English |
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BMC
2025-03-01
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| Series: | BMC Endocrine Disorders |
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| Online Access: | https://doi.org/10.1186/s12902-025-01906-3 |
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| author | Zahra Cheraghi Amin Doosti-Irani Parvin Cheraghi Parham Mohammadi Marzieh Otogara |
| author_facet | Zahra Cheraghi Amin Doosti-Irani Parvin Cheraghi Parham Mohammadi Marzieh Otogara |
| author_sort | Zahra Cheraghi |
| collection | DOAJ |
| description | Abstract Objective The most significant challenge faced by individuals with diabetes is poor blood sugar control. The objective of this review is to identify the most crucial predictors of poor glycemic control among patients with diabetes. Materials This review employed a comprehensive approach, utilizing all available analytical cross-sectional, case control and cohort studies to ascertain the pooled odds ratio/risk ratio of uncontrolled diabetes. The review encompassed articles from international databases, including Web of Science, PubMed, Scopus, and Google Scholar without restrictions on publication date or language. Data extraction was conducted until May 11, 2024, with statistical analyses performed using Stata 17 software, employing a random effects model at a 95% confidence level. Results Out of 157,841 records, a total of 59 cross-sectional studies, 4 case-control studies, and 3 cohort studies were included, comprising 284,558 participants with a mean age of 53.78 years (SD = 6.33). There was no statistically significant association between the seven factors analyzed—age, gender, smoking status, education level, systolic blood pressure, diastolic blood pressure, and BMI. However, we observed a significant decrease in the likelihood of poor glycemic control with each unit increase in physical activity. Specifically, as physical activity levels increased, the likelihood of poor glycemic control decreased (adjusted OR 0.41; 95% CI: 0.24, 0.72; p-value = 0.02). Conclusion Our systematic review and meta-analysis study showed that increased levels of physical activity in individuals with type 2 diabetes enhance the chances of achieving better glycemic control. |
| format | Article |
| id | doaj-art-78414e3386ed4c5aa1e2f7bbe5cc2775 |
| institution | Kabale University |
| issn | 1472-6823 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj-art-78414e3386ed4c5aa1e2f7bbe5cc27752025-08-20T03:40:49ZengBMCBMC Endocrine Disorders1472-68232025-03-012511910.1186/s12902-025-01906-3Predictor factors of uncontrolled diabetesZahra Cheraghi0Amin Doosti-Irani1Parvin Cheraghi2Parham Mohammadi3Marzieh Otogara4Modeling of Noncommunicable Diseases Research Center, Institute of Health Sciences and Technologies, Avicenna Health Research Institute, Hamadan University of Medical SciencesResearch Center for Health Sciences, Institute of Health Sciences and Technologies, Avicenna Health Research Institute, Hamadan University of Medical SciencesDepartment of Health Education and Promotion, School of Public Health, Hamadan University of Medical SciencesDepartment of Epidemiology, School of Public Health, Hamadan University of Medical SciencesMother and Child Care Research Center, Institute of Health Sciences and Technologies, Avicenna Health Research Institute, Hamadan University of Medical SciencesAbstract Objective The most significant challenge faced by individuals with diabetes is poor blood sugar control. The objective of this review is to identify the most crucial predictors of poor glycemic control among patients with diabetes. Materials This review employed a comprehensive approach, utilizing all available analytical cross-sectional, case control and cohort studies to ascertain the pooled odds ratio/risk ratio of uncontrolled diabetes. The review encompassed articles from international databases, including Web of Science, PubMed, Scopus, and Google Scholar without restrictions on publication date or language. Data extraction was conducted until May 11, 2024, with statistical analyses performed using Stata 17 software, employing a random effects model at a 95% confidence level. Results Out of 157,841 records, a total of 59 cross-sectional studies, 4 case-control studies, and 3 cohort studies were included, comprising 284,558 participants with a mean age of 53.78 years (SD = 6.33). There was no statistically significant association between the seven factors analyzed—age, gender, smoking status, education level, systolic blood pressure, diastolic blood pressure, and BMI. However, we observed a significant decrease in the likelihood of poor glycemic control with each unit increase in physical activity. Specifically, as physical activity levels increased, the likelihood of poor glycemic control decreased (adjusted OR 0.41; 95% CI: 0.24, 0.72; p-value = 0.02). Conclusion Our systematic review and meta-analysis study showed that increased levels of physical activity in individuals with type 2 diabetes enhance the chances of achieving better glycemic control.https://doi.org/10.1186/s12902-025-01906-3Type 2 diabetes mellitusGlycemic controlPredictor factorsSystematic review and meta-analysis |
| spellingShingle | Zahra Cheraghi Amin Doosti-Irani Parvin Cheraghi Parham Mohammadi Marzieh Otogara Predictor factors of uncontrolled diabetes BMC Endocrine Disorders Type 2 diabetes mellitus Glycemic control Predictor factors Systematic review and meta-analysis |
| title | Predictor factors of uncontrolled diabetes |
| title_full | Predictor factors of uncontrolled diabetes |
| title_fullStr | Predictor factors of uncontrolled diabetes |
| title_full_unstemmed | Predictor factors of uncontrolled diabetes |
| title_short | Predictor factors of uncontrolled diabetes |
| title_sort | predictor factors of uncontrolled diabetes |
| topic | Type 2 diabetes mellitus Glycemic control Predictor factors Systematic review and meta-analysis |
| url | https://doi.org/10.1186/s12902-025-01906-3 |
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