Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus
Diffuse alveolar hemorrhage (DAH) is a rare life-threatening complication in systemic lupus erythematosus (SLE) associated with high mortality rates. DAH is more common in women, and mean age of onset is around 30 years. It mostly occurs in patients with established diagnosis of SLE but can be the i...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2012/836017 |
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| author | Ravi Paul Singh Virdi Adeel Bashir Ghulamullah Shahzad Javed Iqbal Jose O. Mejia |
| author_facet | Ravi Paul Singh Virdi Adeel Bashir Ghulamullah Shahzad Javed Iqbal Jose O. Mejia |
| author_sort | Ravi Paul Singh Virdi |
| collection | DOAJ |
| description | Diffuse alveolar hemorrhage (DAH) is a rare life-threatening complication in systemic lupus erythematosus (SLE) associated with high mortality rates. DAH is more common in women, and mean age of onset is around 30 years. It mostly occurs in patients with established diagnosis of SLE but can be the initial presentation of lupus in approximately 20%. DAH should be suspected in lupus patient presenting with new pulmonary infiltrates, decline in hemoglobin, hemoptysis, dyspnea, hypoxemia, and increase in carbon monoxide diffusion capacity. Radiographic evidence of bilateral pulmonary alveolar infiltrates that are usually perihilar or basilar with sparing of apices is seen. DAH can often mimic clinically and radiologically severe pneumonia or ARDS. Treatment includes high-dose corticosteroids, cyclophosphamide, and plasmapheresis. We report a case of diffuse alveolar hemorrhage complicating SLE flare-up in a male patient. |
| format | Article |
| id | doaj-art-783b7afb390445b09e02ad1c90efcd99 |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-783b7afb390445b09e02ad1c90efcd992025-08-20T03:35:11ZengWileyCase Reports in Pulmonology2090-68462090-68542012-01-01201210.1155/2012/836017836017Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus ErythematosusRavi Paul Singh Virdi0Adeel Bashir1Ghulamullah Shahzad2Javed Iqbal3Jose O. Mejia4Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADiffuse alveolar hemorrhage (DAH) is a rare life-threatening complication in systemic lupus erythematosus (SLE) associated with high mortality rates. DAH is more common in women, and mean age of onset is around 30 years. It mostly occurs in patients with established diagnosis of SLE but can be the initial presentation of lupus in approximately 20%. DAH should be suspected in lupus patient presenting with new pulmonary infiltrates, decline in hemoglobin, hemoptysis, dyspnea, hypoxemia, and increase in carbon monoxide diffusion capacity. Radiographic evidence of bilateral pulmonary alveolar infiltrates that are usually perihilar or basilar with sparing of apices is seen. DAH can often mimic clinically and radiologically severe pneumonia or ARDS. Treatment includes high-dose corticosteroids, cyclophosphamide, and plasmapheresis. We report a case of diffuse alveolar hemorrhage complicating SLE flare-up in a male patient.http://dx.doi.org/10.1155/2012/836017 |
| spellingShingle | Ravi Paul Singh Virdi Adeel Bashir Ghulamullah Shahzad Javed Iqbal Jose O. Mejia Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus Case Reports in Pulmonology |
| title | Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus |
| title_full | Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus |
| title_fullStr | Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus |
| title_full_unstemmed | Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus |
| title_short | Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus |
| title_sort | diffuse alveolar hemorrhage a rare life threatening condition in systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2012/836017 |
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