Development of a clinical prediction model for sensitivity to combination therapy of Bcl-2 inhibitors and hypomethylating agents in elderly/unfit patients with acute myeloid leukemia

Abstract Objective This study aims to develop a clinical prediction model for sensitivity to Bcl-2 inhibitors combined with hypomethylating agents (HMAs) in elderly/unfit patients with acute myeloid leukemia (AML). Methods Clinical data, including French-American-British (FAB) classification, chromo...

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Bibliographic Details
Main Authors: Yufeng Du, Chunhong Li, Yonghong Chen, Fang Xie, Jinsong Yan
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02612-1
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