Iron Fist in a Velvet Glove: Class IV Ferroptosis Inducers as a Novel Strategy to Target Ovarian Cancer

Iron Fist in a Velvet Glove: Class IV Ferroptosis Inducers as a Novel Strategy to Target Ovarian Cancer

Epithelial ovarian cancer (EOC) is a highly lethal gynecological malignancy characterized by frequent late-stage diagnosis, high rates of chemoresistance, and poor long-term survival. Emerging evidence underscores the central role of iron metabolism dysregulation in EOC pathogenesis, progression, an...

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Main Authors: Lavinia Petriaggi, Emanuele Giorgio, Giuseppe Natali, Cristiana Galeano, Simão Rodrigues Furtado, Concetta Maria Faniello, Francesco Saverio Costanzo, Flavia Biamonte, Anna Martina Battaglia
Format: Article
Language:English
Published: IMR Press 2025-07-01
Series:Frontiers in Bioscience-Landmark
Subjects:
epithelial ovarian cancer
ferroptosis
metabolism
iron compounds
Online Access:https://www.imrpress.com/journal/FBL/30/7/10.31083/FBL39675
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