Population pharmacokinetic analysis of remimazolam after continuous infusion for sedation in critically ill patients

Population pharmacokinetic analysis of remimazolam after continuous infusion for sedation in critically ill patients

IntroductionThe aim of the present prospective study was to model the population pharmacokinetics of remimazolam after continuous infusion in critically ill patients, and to provide a guide for remimazolam administration based on simulations that were conducted.Patients and methodsA total of 32 crit...

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Main Authors: Jingchun Chen, Xipei Wang, Dong Chen, Xiaolong Liu, Kaiyi Peng, Ruizheng Tang, Linhui Hu, Yirong Wang, Yunpeng Bai, Lin Chang, Chunbo Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
critically ill patients
population pharmacokinetics
remimazolam
sedation
context-sensitive decrement times
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1526266/full
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