The role of kynurenine and kynurenine metabolites in psoriasis

Psoriasis is a widespread immunological disease characterised by inflammation and primarily associated with skin and joint symptoms. The kynurenine pathway significantly influences inflammation and immune system activity. The aim of this study is to determine serum concentrations of kynurenine metab...

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Main Authors: Akyurek Fikret, Tuncez-Akyurek Fatma, Sengul Fatma
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2024-0135
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author Akyurek Fikret
Tuncez-Akyurek Fatma
Sengul Fatma
author_facet Akyurek Fikret
Tuncez-Akyurek Fatma
Sengul Fatma
author_sort Akyurek Fikret
collection DOAJ
description Psoriasis is a widespread immunological disease characterised by inflammation and primarily associated with skin and joint symptoms. The kynurenine pathway significantly influences inflammation and immune system activity. The aim of this study is to determine serum concentrations of kynurenine metabolites in patients with psoriasis and investigate their correlation with disease severity.
format Article
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issn 1303-829X
language English
publishDate 2024-12-01
publisher De Gruyter
record_format Article
series Türk Biyokimya Dergisi
spelling doaj-art-7816504b4e804db49d9c94f796ca9db22025-08-20T02:17:53ZengDe GruyterTürk Biyokimya Dergisi1303-829X2024-12-0150114415110.1515/tjb-2024-0135The role of kynurenine and kynurenine metabolites in psoriasisAkyurek Fikret0Tuncez-Akyurek Fatma1Sengul Fatma2Department of Biochemistry, Faculty of Medicine, Selcuk University, Konya, TürkiyeDepartment of Dermatology, Faculty of Medicine, Selcuk University, Konya, TürkiyeDepartment of Biochemistry, Faculty of Pharmacy, Adıyaman University, Adıyaman, TürkiyePsoriasis is a widespread immunological disease characterised by inflammation and primarily associated with skin and joint symptoms. The kynurenine pathway significantly influences inflammation and immune system activity. The aim of this study is to determine serum concentrations of kynurenine metabolites in patients with psoriasis and investigate their correlation with disease severity.https://doi.org/10.1515/tjb-2024-0135psoriasiskynurenine pathwaytryptophan to kynurenine ratiohs-crppasi
spellingShingle Akyurek Fikret
Tuncez-Akyurek Fatma
Sengul Fatma
The role of kynurenine and kynurenine metabolites in psoriasis
Türk Biyokimya Dergisi
psoriasis
kynurenine pathway
tryptophan to kynurenine ratio
hs-crp
pasi
title The role of kynurenine and kynurenine metabolites in psoriasis
title_full The role of kynurenine and kynurenine metabolites in psoriasis
title_fullStr The role of kynurenine and kynurenine metabolites in psoriasis
title_full_unstemmed The role of kynurenine and kynurenine metabolites in psoriasis
title_short The role of kynurenine and kynurenine metabolites in psoriasis
title_sort role of kynurenine and kynurenine metabolites in psoriasis
topic psoriasis
kynurenine pathway
tryptophan to kynurenine ratio
hs-crp
pasi
url https://doi.org/10.1515/tjb-2024-0135
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