Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components
ABSTRACT Lactose, milk fat, and milk protein are the primary nutritional components of milk. They serve as key indicators for assessing its nutritional value and are closely linked to the economic benefits of the dairy industry. The mammalian target of rapamycin (mTOR) pathway plays a crucial role i...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2025-06-01
|
| Series: | Modern Agriculture |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/moda.70009 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849425309684727808 |
|---|---|
| author | RongNuo Li YiNing Zheng HuiJun Geng Lu Deng |
| author_facet | RongNuo Li YiNing Zheng HuiJun Geng Lu Deng |
| author_sort | RongNuo Li |
| collection | DOAJ |
| description | ABSTRACT Lactose, milk fat, and milk protein are the primary nutritional components of milk. They serve as key indicators for assessing its nutritional value and are closely linked to the economic benefits of the dairy industry. The mammalian target of rapamycin (mTOR) pathway plays a crucial role in regulating cellular growth and proliferation by modulating the synthesis of proteins, lipids, and nucleotides, while concurrently suppressing catabolic processes such as autophagy. This pathway is particularly imperative for ensuring efficient and healthy reproduction in dairy cows and beef cattle. Therefore, the present paper provides a comprehensive review of the mechanisms underlying the synthesis of lactose, milk fat, and milk protein, with particular emphasis on the role of the mTOR signalling pathway in regulating milk component synthesis. These findings lay a theoretical basis for further studies into the roles of mTOR and offer valuable insights for enhancing nutritional regulation strategies aimed at improving milk component composition. Importantly, they suggest that targeting the mTOR signalling pathway to promote efficient and healthy farming of dairy cattle may be a potential strategy to boost livestock industry profits. |
| format | Article |
| id | doaj-art-77f2fb26318e48b8934e7cf15894a532 |
| institution | Kabale University |
| issn | 2751-4102 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Modern Agriculture |
| spelling | doaj-art-77f2fb26318e48b8934e7cf15894a5322025-08-20T03:29:48ZengWiley-VCHModern Agriculture2751-41022025-06-0131n/an/a10.1002/moda.70009Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk ComponentsRongNuo Li0YiNing Zheng1HuiJun Geng2Lu Deng3College of Animal Science and Technology Northwest A&F University Yangling ChinaCollege of Animal Science and Technology Northwest A&F University Yangling ChinaCollege of Animal Science and Technology Northwest A&F University Yangling ChinaCollege of Animal Science and Technology Northwest A&F University Yangling ChinaABSTRACT Lactose, milk fat, and milk protein are the primary nutritional components of milk. They serve as key indicators for assessing its nutritional value and are closely linked to the economic benefits of the dairy industry. The mammalian target of rapamycin (mTOR) pathway plays a crucial role in regulating cellular growth and proliferation by modulating the synthesis of proteins, lipids, and nucleotides, while concurrently suppressing catabolic processes such as autophagy. This pathway is particularly imperative for ensuring efficient and healthy reproduction in dairy cows and beef cattle. Therefore, the present paper provides a comprehensive review of the mechanisms underlying the synthesis of lactose, milk fat, and milk protein, with particular emphasis on the role of the mTOR signalling pathway in regulating milk component synthesis. These findings lay a theoretical basis for further studies into the roles of mTOR and offer valuable insights for enhancing nutritional regulation strategies aimed at improving milk component composition. Importantly, they suggest that targeting the mTOR signalling pathway to promote efficient and healthy farming of dairy cattle may be a potential strategy to boost livestock industry profits.https://doi.org/10.1002/moda.70009lactosemilk fatmilk proteinsmTOR |
| spellingShingle | RongNuo Li YiNing Zheng HuiJun Geng Lu Deng Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components Modern Agriculture lactose milk fat milk proteins mTOR |
| title | Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components |
| title_full | Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components |
| title_fullStr | Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components |
| title_full_unstemmed | Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components |
| title_short | Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components |
| title_sort | role and mechanisms of the mtor signalling pathway in the synthesis of milk components |
| topic | lactose milk fat milk proteins mTOR |
| url | https://doi.org/10.1002/moda.70009 |
| work_keys_str_mv | AT rongnuoli roleandmechanismsofthemtorsignallingpathwayinthesynthesisofmilkcomponents AT yiningzheng roleandmechanismsofthemtorsignallingpathwayinthesynthesisofmilkcomponents AT huijungeng roleandmechanismsofthemtorsignallingpathwayinthesynthesisofmilkcomponents AT ludeng roleandmechanismsofthemtorsignallingpathwayinthesynthesisofmilkcomponents |