Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT
Extraadrenal chromaffin cell-related tumors or paragangliomas are rare, especially in the bladder, accounting for less than 1% of cases. We report a 16-year-old boy who presented with hematuria and paroxysmal headache and was found to have a prostatic growth infiltrating the urinary bladder on anato...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2016-01-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167591 |
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| author | Tarun Jain Rajender Basher Nitin Gupta Jaya Shukla Shrawan Singh Bhagwant Mittal |
| author_facet | Tarun Jain Rajender Basher Nitin Gupta Jaya Shukla Shrawan Singh Bhagwant Mittal |
| author_sort | Tarun Jain |
| collection | DOAJ |
| description | Extraadrenal chromaffin cell-related tumors or paragangliomas are rare, especially in the bladder, accounting for less than 1% of cases. We report a 16-year-old boy who presented with hematuria and paroxysmal headache and was found to have a prostatic growth infiltrating the urinary bladder on anatomical imaging. Iodine-131 (131I) metaiodobenzylguanidine (MIBG) whole-body scanning and subsequently gallium-68 (68Ga) DOTANOC positron emission tomography/computed tomography (PET/CT) were performed. The MIBG scan revealed a non-tracer-avid soft-tissue mass, while DOTANOC PET/CT revealed a tracer-avid primary soft-tissue mass involving the urinary bladder and prostate with metastasis to the iliac lymph nodes. He underwent surgical management; histopathology of the surgical specimen revealed a bladder paraganglioma, whereas the prostate was found to be free of tumor. |
| format | Article |
| id | doaj-art-77f2e668dfc94698bb1a0fb0268ee6c3 |
| institution | OA Journals |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
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| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-77f2e668dfc94698bb1a0fb0268ee6c32025-08-20T01:57:55ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122016-01-011501656710.4103/1450-1147.167591Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CTTarun Jain0Rajender Basher1Nitin Gupta2Jaya Shukla3Shrawan Singh4Bhagwant Mittal5Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaDepartment of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, IndiaExtraadrenal chromaffin cell-related tumors or paragangliomas are rare, especially in the bladder, accounting for less than 1% of cases. We report a 16-year-old boy who presented with hematuria and paroxysmal headache and was found to have a prostatic growth infiltrating the urinary bladder on anatomical imaging. Iodine-131 (131I) metaiodobenzylguanidine (MIBG) whole-body scanning and subsequently gallium-68 (68Ga) DOTANOC positron emission tomography/computed tomography (PET/CT) were performed. The MIBG scan revealed a non-tracer-avid soft-tissue mass, while DOTANOC PET/CT revealed a tracer-avid primary soft-tissue mass involving the urinary bladder and prostate with metastasis to the iliac lymph nodes. He underwent surgical management; histopathology of the surgical specimen revealed a bladder paraganglioma, whereas the prostate was found to be free of tumor.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167591bladder paragangliomaiodine-131 (131i) metaiodobenzylguanidine (mibg)gallium-68 (68ga) dotanoc positron emission tomography.computed tomography. (pet/ct) |
| spellingShingle | Tarun Jain Rajender Basher Nitin Gupta Jaya Shukla Shrawan Singh Bhagwant Mittal Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT World Journal of Nuclear Medicine bladder paraganglioma iodine-131 (131i) metaiodobenzylguanidine (mibg) gallium-68 (68ga) dotanoc positron emission tomography.computed tomography. (pet/ct) |
| title | Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT |
| title_full | Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT |
| title_fullStr | Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT |
| title_full_unstemmed | Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT |
| title_short | Unusual presentation of bladder paraganglioma: Comparison of 131I MIBG SPECT/CT and 68Ga DOTANOC PET/CT |
| title_sort | unusual presentation of bladder paraganglioma comparison of 131i mibg spect ct and 68ga dotanoc pet ct |
| topic | bladder paraganglioma iodine-131 (131i) metaiodobenzylguanidine (mibg) gallium-68 (68ga) dotanoc positron emission tomography.computed tomography. (pet/ct) |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.167591 |
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