Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification

Inflammatory complications of cataract phacoemulsification are among the most urgent and potentially vision-threatening conditions. Corneal melting is a rare but clinically significant condition preceding corneal perforation. The main risk factors are the use of nonsteroidal anti-inflammatory drugs...

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Main Authors: S. N. Svetozarskiy, A. N. Andreev, A. V. Shvaikin, I. G. Smetankin
Format: Article
Language:Russian
Published: Real Time Ltd 2023-10-01
Series:Российский офтальмологический журнал
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Online Access:https://roj.igb.ru/jour/article/view/1310
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author S. N. Svetozarskiy
A. N. Andreev
A. V. Shvaikin
I. G. Smetankin
author_facet S. N. Svetozarskiy
A. N. Andreev
A. V. Shvaikin
I. G. Smetankin
author_sort S. N. Svetozarskiy
collection DOAJ
description Inflammatory complications of cataract phacoemulsification are among the most urgent and potentially vision-threatening conditions. Corneal melting is a rare but clinically significant condition preceding corneal perforation. The main risk factors are the use of nonsteroidal anti-inflammatory drugs (NSAIDs), severe dry eye disease and rheumatic diseases. The paper presents a literature review and offers an analysis of a clinical case of corneal melting after cataract phacoemulsification in a female patient with severe dry eye disease, which was undiagnosed before surgery. The follow-up period was 5 years. The possibilities and limitations of multiple methods of corneal melting treatment at the stages of persistent epithelial defect and corneal ulcer are discussed. The mechanism of disease development and its link with the pathogenesis of dry eye disease and the role of topical NSAIDs as a trigger for the initiation and progression of corneal melting are considered.
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issn 2072-0076
2587-5760
language Russian
publishDate 2023-10-01
publisher Real Time Ltd
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series Российский офтальмологический журнал
spelling doaj-art-77f0c87f262c4646a6ceed0742e7fbd92025-08-20T03:19:24ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602023-10-0116312713510.21516/2072-0076-2023-16-3-127-135621Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsificationS. N. Svetozarskiy0A. N. Andreev1A. V. Shvaikin2I. G. Smetankin3Volga District Medical Center, Federal Medical and Biological Agency; Volga District Medical UniversityVolga District Medical Center, Federal Medical and Biological AgencyVolga District Medical Center, Federal Medical and Biological AgencyVolga District Medical Center, Federal Medical and Biological Agency; Volga District Medical UniversityInflammatory complications of cataract phacoemulsification are among the most urgent and potentially vision-threatening conditions. Corneal melting is a rare but clinically significant condition preceding corneal perforation. The main risk factors are the use of nonsteroidal anti-inflammatory drugs (NSAIDs), severe dry eye disease and rheumatic diseases. The paper presents a literature review and offers an analysis of a clinical case of corneal melting after cataract phacoemulsification in a female patient with severe dry eye disease, which was undiagnosed before surgery. The follow-up period was 5 years. The possibilities and limitations of multiple methods of corneal melting treatment at the stages of persistent epithelial defect and corneal ulcer are discussed. The mechanism of disease development and its link with the pathogenesis of dry eye disease and the role of topical NSAIDs as a trigger for the initiation and progression of corneal melting are considered.https://roj.igb.ru/jour/article/view/1310keratomalaciacataract extractionpostoperative complicationsinflammationdry eye diseasecorneal ulceration
spellingShingle S. N. Svetozarskiy
A. N. Andreev
A. V. Shvaikin
I. G. Smetankin
Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
Российский офтальмологический журнал
keratomalacia
cataract extraction
postoperative complications
inflammation
dry eye disease
corneal ulceration
title Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
title_full Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
title_fullStr Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
title_full_unstemmed Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
title_short Risk factors, diagnostics and treatment of corneal melting after cataract phacoemulsification
title_sort risk factors diagnostics and treatment of corneal melting after cataract phacoemulsification
topic keratomalacia
cataract extraction
postoperative complications
inflammation
dry eye disease
corneal ulceration
url https://roj.igb.ru/jour/article/view/1310
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AT anandreev riskfactorsdiagnosticsandtreatmentofcornealmeltingaftercataractphacoemulsification
AT avshvaikin riskfactorsdiagnosticsandtreatmentofcornealmeltingaftercataractphacoemulsification
AT igsmetankin riskfactorsdiagnosticsandtreatmentofcornealmeltingaftercataractphacoemulsification