Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma
Here, we describe the case of a 66-year-old male diagnosed with multiple myeloma who presented with generalized tonic-clonic seizures. Magnetic resonance imaging demonstrated a right solid extra-axial parieto-occipital lesion with typical characteristics of meningeal myelomatosis. Biopsy was perform...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/6730567 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558043921907712 |
|---|---|
| author | Nieves Gascón Héctor Pérez-Montero Sandra Guardado Rafael D’Ambrosi María Ángeles Cabeza José Fermín Pérez-Regadera |
| author_facet | Nieves Gascón Héctor Pérez-Montero Sandra Guardado Rafael D’Ambrosi María Ángeles Cabeza José Fermín Pérez-Regadera |
| author_sort | Nieves Gascón |
| collection | DOAJ |
| description | Here, we describe the case of a 66-year-old male diagnosed with multiple myeloma who presented with generalized tonic-clonic seizures. Magnetic resonance imaging demonstrated a right solid extra-axial parieto-occipital lesion with typical characteristics of meningeal myelomatosis. Biopsy was performed, which diagnosed a dural plasmacytoma. Because of this, we started concomitant therapy with radiotherapy and lenalidomide, but the patient has a poor response to treatment and died few weeks after its initiation. Myelomatous involvement of the dura mater is a rare occurrence, given that only few cases were reported in the English literature. This presentation confers an ominous prognosis and must be a suspect diagnosis in patients diagnosed with multiple myeloma presenting neurological symptoms. |
| format | Article |
| id | doaj-art-77f01a6965e34f7e8daaa3d467f1d1f8 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-77f01a6965e34f7e8daaa3d467f1d1f82025-02-03T01:33:25ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/67305676730567Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple MyelomaNieves Gascón0Héctor Pérez-Montero1Sandra Guardado2Rafael D’Ambrosi3María Ángeles Cabeza4José Fermín Pérez-Regadera5Radiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainRadiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainRadiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainRadiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainRadiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainRadiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, SpainHere, we describe the case of a 66-year-old male diagnosed with multiple myeloma who presented with generalized tonic-clonic seizures. Magnetic resonance imaging demonstrated a right solid extra-axial parieto-occipital lesion with typical characteristics of meningeal myelomatosis. Biopsy was performed, which diagnosed a dural plasmacytoma. Because of this, we started concomitant therapy with radiotherapy and lenalidomide, but the patient has a poor response to treatment and died few weeks after its initiation. Myelomatous involvement of the dura mater is a rare occurrence, given that only few cases were reported in the English literature. This presentation confers an ominous prognosis and must be a suspect diagnosis in patients diagnosed with multiple myeloma presenting neurological symptoms.http://dx.doi.org/10.1155/2018/6730567 |
| spellingShingle | Nieves Gascón Héctor Pérez-Montero Sandra Guardado Rafael D’Ambrosi María Ángeles Cabeza José Fermín Pérez-Regadera Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma Case Reports in Hematology |
| title | Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma |
| title_full | Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma |
| title_fullStr | Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma |
| title_full_unstemmed | Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma |
| title_short | Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma |
| title_sort | dural plasmacytoma with meningeal myelomatosis in a patient with multiple myeloma |
| url | http://dx.doi.org/10.1155/2018/6730567 |
| work_keys_str_mv | AT nievesgascon duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma AT hectorperezmontero duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma AT sandraguardado duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma AT rafaeldambrosi duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma AT mariaangelescabeza duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma AT joseferminperezregadera duralplasmacytomawithmeningealmyelomatosisinapatientwithmultiplemyeloma |