Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa
Our phytochemical study focused on the leaves of Citrus deliciosa of Algerian origin, in order to evaluate its antioxidant activity and its acute toxicity, using scavenger activity of DPPH radicals, ABTS and acute toxicity. The ethanol extract of Citrus deliciosa contains 85.62 ± 2.24 μg /mg dried...
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| Format: | Article |
| Language: | English |
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Hasan Eleroğlu
2023-06-01
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| Series: | Turkish Journal of Agriculture: Food Science and Technology |
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| Online Access: | http://www.agrifoodscience.com/index.php/TURJAF/article/view/5984 |
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| author | Nasri Meriem Touati Noureddine Abed Hanane |
| author_facet | Nasri Meriem Touati Noureddine Abed Hanane |
| author_sort | Nasri Meriem |
| collection | DOAJ |
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Our phytochemical study focused on the leaves of Citrus deliciosa of Algerian origin, in order to evaluate its antioxidant activity and its acute toxicity, using scavenger activity of DPPH radicals, ABTS and acute toxicity. The ethanol extract of Citrus deliciosa contains 85.62 ± 2.24 μg /mg dried matter and 3.02 ± 0.17 μg/mg dried matter. The antioxidant activity was confirmed against the DPPH radical (IC50 = 252.07 ± 0.02 μg /mL) and ABTS (IC50 = 398.26 ± 0.01 μg /mL). No mortality or abnormal behavior was observed in mice at oral doses less of 1600 mg/kg. According to the results obtained, Citrus deliciosa leaves exhibit significant antioxidant activity and are safe at levels lower than 1600 mg/kg B.W., which supports their application in phytotherapy, pharmaceutical biotechnology, and the food sector for therapeutic or preventive purposes.
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| format | Article |
| id | doaj-art-77eb7ad23fdb4cce950e3679f32fea60 |
| institution | OA Journals |
| issn | 2148-127X |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Hasan Eleroğlu |
| record_format | Article |
| series | Turkish Journal of Agriculture: Food Science and Technology |
| spelling | doaj-art-77eb7ad23fdb4cce950e3679f32fea602025-08-20T01:57:55ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2023-06-0111610.24925/turjaf.v11i6.1106-1109.59844686Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosaNasri Meriem0Touati Noureddine1Abed Hanane2Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. AlgeriaLaboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria.Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. Our phytochemical study focused on the leaves of Citrus deliciosa of Algerian origin, in order to evaluate its antioxidant activity and its acute toxicity, using scavenger activity of DPPH radicals, ABTS and acute toxicity. The ethanol extract of Citrus deliciosa contains 85.62 ± 2.24 μg /mg dried matter and 3.02 ± 0.17 μg/mg dried matter. The antioxidant activity was confirmed against the DPPH radical (IC50 = 252.07 ± 0.02 μg /mL) and ABTS (IC50 = 398.26 ± 0.01 μg /mL). No mortality or abnormal behavior was observed in mice at oral doses less of 1600 mg/kg. According to the results obtained, Citrus deliciosa leaves exhibit significant antioxidant activity and are safe at levels lower than 1600 mg/kg B.W., which supports their application in phytotherapy, pharmaceutical biotechnology, and the food sector for therapeutic or preventive purposes. http://www.agrifoodscience.com/index.php/TURJAF/article/view/5984Ethanol extractCitrus deliciosaantioxidant activityacute toxicityflavonoids. |
| spellingShingle | Nasri Meriem Touati Noureddine Abed Hanane Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa Turkish Journal of Agriculture: Food Science and Technology Ethanol extract Citrus deliciosa antioxidant activity acute toxicity flavonoids. |
| title | Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa |
| title_full | Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa |
| title_fullStr | Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa |
| title_full_unstemmed | Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa |
| title_short | Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa |
| title_sort | acute toxicity and antioxidant activity of algerian citrus deliciosa |
| topic | Ethanol extract Citrus deliciosa antioxidant activity acute toxicity flavonoids. |
| url | http://www.agrifoodscience.com/index.php/TURJAF/article/view/5984 |
| work_keys_str_mv | AT nasrimeriem acutetoxicityandantioxidantactivityofalgeriancitrusdeliciosa AT touatinoureddine acutetoxicityandantioxidantactivityofalgeriancitrusdeliciosa AT abedhanane acutetoxicityandantioxidantactivityofalgeriancitrusdeliciosa |