Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009

Background/Aim. Lip, oral cavity and pharynx malignant tumors account for 3.7% of all cancer deaths worldwide, with significant geographic variations in frequency and distribution. The aim of this descriptive epidemiologic study was to analyze the mortality rate of lip, oral cavity and phar...

Full description

Saved in:
Bibliographic Details
Main Authors: Ilić Milena, Radević Svetlana, Stefanović Vladimir, Ćirković Tatjana, Zurovac Tamara, Savić Borivoje, Kovačević Vladan
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2013-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501302189I.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850220160147783680
author Ilić Milena
Radević Svetlana
Stefanović Vladimir
Ćirković Tatjana
Zurovac Tamara
Savić Borivoje
Kovačević Vladan
author_facet Ilić Milena
Radević Svetlana
Stefanović Vladimir
Ćirković Tatjana
Zurovac Tamara
Savić Borivoje
Kovačević Vladan
author_sort Ilić Milena
collection DOAJ
description Background/Aim. Lip, oral cavity and pharynx malignant tumors account for 3.7% of all cancer deaths worldwide, with significant geographic variations in frequency and distribution. The aim of this descriptive epidemiologic study was to analyze the mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia proper within a period 1991-2009. Methods. Mortality rates standardized directly using the world population as the standard were used in data analysis. Linear trend and regression analyses were used to analyze rate trends in mortality. Results. The Serbian population demonstrated an increase in the mortality of lip, oral cavity and pharynx malignant tumors (y = 3.32 + 0.03×; p = 0.002; average annual percent change = + 0.8). The male population showed a significant increase in mortality trend (y = 5.90 + 0.03×; p = 0.020; % change = + 0.9), while the female population did not show a significant increase in mortality. The male/female cancer mortality ratio was 5.5:1. Mortality rates for lip, oral cavity and pharynx cancer increased with age in both genders, with rates being the highest in the population aged 85 and older. Increasing trends of lip, oral cavity and pharynx cancer mortality were observed in males aged 50-54; the average annual percent change was + 7.4 % (95% CI, 6.2-9.0). The population of both genders aged 55-59 demonstrated an increase in lip, oral cavity and pharynx cancer mortality, the increase being + 1.8% (95% CI, 1.4-2.2) in men and + 34.3% (95% CI, 28.4-40.2) in women. Conclusion. The increasing trend in lip, oral cavity and pharynx cancer mortality points to the necessity to investigate etiology and improve primary and secondary prevention measures.
format Article
id doaj-art-77e1a0e400f84c1089cbcb86161f7b47
institution OA Journals
issn 0042-8450
language English
publishDate 2013-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
series Vojnosanitetski Pregled
spelling doaj-art-77e1a0e400f84c1089cbcb86161f7b472025-08-20T02:07:09ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502013-01-0170218919410.2298/VSP1302189I0042-84501302189IMortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009Ilić Milena0Radević Svetlana1Stefanović Vladimir2Ćirković Tatjana3Zurovac Tamara4Savić Borivoje5Kovačević Vladan6Faculty of Medicine, Department of Epidemiology, KragujevacFaculty of Medicine, Department of Social Medicine, KragujevacDental Clinic, Military Medical Academy, BelgradeDental Clinic, Military Medical Academy, BelgradeDental Clinic, Military Medical Academy, BelgradeCentre for Nuclear Medicine, Clinical Centre of Serbia, BelgradeDental Clinic, Military Medical Academy, BelgradeBackground/Aim. Lip, oral cavity and pharynx malignant tumors account for 3.7% of all cancer deaths worldwide, with significant geographic variations in frequency and distribution. The aim of this descriptive epidemiologic study was to analyze the mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia proper within a period 1991-2009. Methods. Mortality rates standardized directly using the world population as the standard were used in data analysis. Linear trend and regression analyses were used to analyze rate trends in mortality. Results. The Serbian population demonstrated an increase in the mortality of lip, oral cavity and pharynx malignant tumors (y = 3.32 + 0.03×; p = 0.002; average annual percent change = + 0.8). The male population showed a significant increase in mortality trend (y = 5.90 + 0.03×; p = 0.020; % change = + 0.9), while the female population did not show a significant increase in mortality. The male/female cancer mortality ratio was 5.5:1. Mortality rates for lip, oral cavity and pharynx cancer increased with age in both genders, with rates being the highest in the population aged 85 and older. Increasing trends of lip, oral cavity and pharynx cancer mortality were observed in males aged 50-54; the average annual percent change was + 7.4 % (95% CI, 6.2-9.0). The population of both genders aged 55-59 demonstrated an increase in lip, oral cavity and pharynx cancer mortality, the increase being + 1.8% (95% CI, 1.4-2.2) in men and + 34.3% (95% CI, 28.4-40.2) in women. Conclusion. The increasing trend in lip, oral cavity and pharynx cancer mortality points to the necessity to investigate etiology and improve primary and secondary prevention measures.http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501302189I.pdfmouth neoplasmspharyngeal neoplasmsSerbiamortalityrisk factors
spellingShingle Ilić Milena
Radević Svetlana
Stefanović Vladimir
Ćirković Tatjana
Zurovac Tamara
Savić Borivoje
Kovačević Vladan
Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
Vojnosanitetski Pregled
mouth neoplasms
pharyngeal neoplasms
Serbia
mortality
risk factors
title Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
title_full Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
title_fullStr Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
title_full_unstemmed Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
title_short Mortality rate of lip, oral cavity and pharynx malignant tumors in Serbia within a period 1991-2009
title_sort mortality rate of lip oral cavity and pharynx malignant tumors in serbia within a period 1991 2009
topic mouth neoplasms
pharyngeal neoplasms
Serbia
mortality
risk factors
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501302189I.pdf
work_keys_str_mv AT ilicmilena mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT radevicsvetlana mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT stefanovicvladimir mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT cirkovictatjana mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT zurovactamara mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT savicborivoje mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009
AT kovacevicvladan mortalityrateofliporalcavityandpharynxmalignanttumorsinserbiawithinaperiod19912009