Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child
Aim of investigation. To detect phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundice in relation to gender of the patient.Material and methods. The group of full-term children (n=251) with delayed conjugation jaundice was investigated, that have been divided...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2013-12-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1244 |
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| author | O. K. Botvin'yev A. I. Kolotilina I. N. Razumovskaya A. V. Yeremeyeva |
| author_facet | O. K. Botvin'yev A. I. Kolotilina I. N. Razumovskaya A. V. Yeremeyeva |
| author_sort | O. K. Botvin'yev |
| collection | DOAJ |
| description | Aim of investigation. To detect phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundice in relation to gender of the patient.Material and methods. The group of full-term children (n=251) with delayed conjugation jaundice was investigated, that have been divided in two subgroups according to gender. All patients underwent complex clinical and laboratory, instrumental and immunologic investigation. Features of pregnancy and delivery course, weight and height scores and children disease spectrum, blood groups and Rhesus factor were investigated.Results. It was known, that prevailing genotypic changes in boys – increased proportion of 0 (I) groups and decreased proportion of A (II) blood group, as well as increase of proportion of phenotypes 0 Rh + and decrease of A Rh + in boys prevail in comparison to girls and control group, while in girls environmental factors (complicated course of pregnancy and delivery) have more pronounced effect. Boys and girls differ by disease spectrum. Assessment of these diseases shows, that state of girls was more severe.Conclusions. The original study allows to conclude, that children with delayed conjugation jaundice in neonatal period belong to risk group for development of complications at action of harmful external factors over the liver. |
| format | Article |
| id | doaj-art-77d78736203f49e1bcd8f7b0e48f3af2 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2013-12-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-77d78736203f49e1bcd8f7b0e48f3af22025-02-10T16:14:33ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-12-012362934827Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the childO. K. Botvin'yev0A. I. Kolotilina1I. N. Razumovskaya2A. V. Yeremeyeva3State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian FederationState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university», Ministry of Healthcare of the Russian FederationAim of investigation. To detect phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundice in relation to gender of the patient.Material and methods. The group of full-term children (n=251) with delayed conjugation jaundice was investigated, that have been divided in two subgroups according to gender. All patients underwent complex clinical and laboratory, instrumental and immunologic investigation. Features of pregnancy and delivery course, weight and height scores and children disease spectrum, blood groups and Rhesus factor were investigated.Results. It was known, that prevailing genotypic changes in boys – increased proportion of 0 (I) groups and decreased proportion of A (II) blood group, as well as increase of proportion of phenotypes 0 Rh + and decrease of A Rh + in boys prevail in comparison to girls and control group, while in girls environmental factors (complicated course of pregnancy and delivery) have more pronounced effect. Boys and girls differ by disease spectrum. Assessment of these diseases shows, that state of girls was more severe.Conclusions. The original study allows to conclude, that children with delayed conjugation jaundice in neonatal period belong to risk group for development of complications at action of harmful external factors over the liver.https://www.gastro-j.ru/jour/article/view/1244conjugation jaundicenewbornblood groupsrhesus factor |
| spellingShingle | O. K. Botvin'yev A. I. Kolotilina I. N. Razumovskaya A. V. Yeremeyeva Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child Российский журнал гастроэнтерологии, гепатологии, колопроктологии conjugation jaundice newborn blood groups rhesus factor |
| title | Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child |
| title_full | Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child |
| title_fullStr | Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child |
| title_full_unstemmed | Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child |
| title_short | Phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundices in relation to gender of the child |
| title_sort | phenotypic and genotypic features of the full term newborns with delayed conjugation jaundices in relation to gender of the child |
| topic | conjugation jaundice newborn blood groups rhesus factor |
| url | https://www.gastro-j.ru/jour/article/view/1244 |
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