Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography
Electrochemical behaviour of anticancer drug zileuton was investigated by direct current polarography (DCP) and differential pulse polarography using a dropping mercury electrode (DME) as working electrode and Ag/AgCl reference electrode in universal buffer of pH range from 2.0 to 12.0. The drug was...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/251415 |
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| author | N. Y. Sreedhar M. Sankara Nayak K. Srinivasa Prasad P. R. Prasad C. Nageswar Reddy |
| author_facet | N. Y. Sreedhar M. Sankara Nayak K. Srinivasa Prasad P. R. Prasad C. Nageswar Reddy |
| author_sort | N. Y. Sreedhar |
| collection | DOAJ |
| description | Electrochemical behaviour of anticancer drug zileuton was investigated by direct current polarography (DCP) and differential pulse polarography using a dropping mercury electrode (DME) as working electrode and Ag/AgCl reference electrode in universal buffer of pH range from 2.0 to 12.0. The drug was extracted from the dosage forms in dimethyl formamide (DMF). Kinetic parameters such as diffusion co-efficient (D) and heterogeneous forward rate constants (k0f,h) are evaluated and reported. The differential pulse polarographic method has been developed for the determination of this drug in pharmaceutical formulations. |
| format | Article |
| id | doaj-art-77d76db7adc1402c9d0f729ea1bd81b7 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-77d76db7adc1402c9d0f729ea1bd81b72025-02-03T05:59:49ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017116617010.1155/2010/251415Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by PolarographyN. Y. Sreedhar0M. Sankara Nayak1K. Srinivasa Prasad2P. R. Prasad3C. Nageswar Reddy4Electroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati, A.P, IndiaElectroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati, A.P, IndiaElectroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati, A.P, IndiaElectroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati, A.P, IndiaElectroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati, A.P, IndiaElectrochemical behaviour of anticancer drug zileuton was investigated by direct current polarography (DCP) and differential pulse polarography using a dropping mercury electrode (DME) as working electrode and Ag/AgCl reference electrode in universal buffer of pH range from 2.0 to 12.0. The drug was extracted from the dosage forms in dimethyl formamide (DMF). Kinetic parameters such as diffusion co-efficient (D) and heterogeneous forward rate constants (k0f,h) are evaluated and reported. The differential pulse polarographic method has been developed for the determination of this drug in pharmaceutical formulations.http://dx.doi.org/10.1155/2010/251415 |
| spellingShingle | N. Y. Sreedhar M. Sankara Nayak K. Srinivasa Prasad P. R. Prasad C. Nageswar Reddy Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography E-Journal of Chemistry |
| title | Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography |
| title_full | Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography |
| title_fullStr | Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography |
| title_full_unstemmed | Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography |
| title_short | Electrochemical Reduction Behaviour of Zileuton at a Dropping Mercury Electrode by Polarography |
| title_sort | electrochemical reduction behaviour of zileuton at a dropping mercury electrode by polarography |
| url | http://dx.doi.org/10.1155/2010/251415 |
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