Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis
Objectives: The objective of this study was to compare the efficacy and safety of serratus anterior plane block (SAPB) and thoracic epidural analgesia (TEA) in thoracic region surgery. Materials and Methods: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Tzu Chi Medical Journal |
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| Online Access: | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=4;spage=329;epage=337;aulast=Suhardi |
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| _version_ | 1849409041763139584 |
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| author | Lusianawati Christian Julio Suhardi Christrijogo Sumartono Citrawati Dyah Kencono Wungu |
| author_facet | Lusianawati Christian Julio Suhardi Christrijogo Sumartono Citrawati Dyah Kencono Wungu |
| author_sort | Lusianawati |
| collection | DOAJ |
| description | Objectives: The objective of this study was to compare the efficacy and safety of serratus anterior plane block (SAPB) and thoracic epidural analgesia (TEA) in thoracic region surgery. Materials and Methods: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and through gray literature for all randomized controlled trials that compared SAPB, a novel thoracic wall nerve block, and TEA in surgery. The evaluated outcomes included the Visual Analog Scale (VAS), hypotension, and postoperative nausea and vomiting (PONV). Review Manager, version 5.4.1, was implemented for the analysis of statistics. Results: The pooled analysis included six trials that fulfilled the inclusion criteria. In total 384, surgery had received regional blocks (162 – SAPB and 163 – TEA). VAS did not differ significantly between SAPB and TEA, with a mean difference of 0.71, P = 0.08. PONV incidence did not differ significantly between SAPB and TEA (odds ratio = 0.25, P = 0.07). Hypotension incidence was lower in SAPB compared to TEA (odds ratio = 0.10, P = 0.0001). Conclusion: SAPB yielded comparable VAS with TEA in pain management of thoracic region surgery. The incidence of hypotension was lower in SAPB than in TEA. No difference in PONV incidence was observed. SAPB can be a viable alternative to TEA in thoracic region surgery. |
| format | Article |
| id | doaj-art-77cc34da2a0944d9af901a9970fdb4ea |
| institution | Kabale University |
| issn | 1016-3190 2223-8956 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tzu Chi Medical Journal |
| spelling | doaj-art-77cc34da2a0944d9af901a9970fdb4ea2025-08-20T03:35:37ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562023-01-0135432933710.4103/tcmj.tcmj_36_23Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysisLusianawatiChristian Julio SuhardiChristrijogo SumartonoCitrawati Dyah Kencono WunguObjectives: The objective of this study was to compare the efficacy and safety of serratus anterior plane block (SAPB) and thoracic epidural analgesia (TEA) in thoracic region surgery. Materials and Methods: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and through gray literature for all randomized controlled trials that compared SAPB, a novel thoracic wall nerve block, and TEA in surgery. The evaluated outcomes included the Visual Analog Scale (VAS), hypotension, and postoperative nausea and vomiting (PONV). Review Manager, version 5.4.1, was implemented for the analysis of statistics. Results: The pooled analysis included six trials that fulfilled the inclusion criteria. In total 384, surgery had received regional blocks (162 – SAPB and 163 – TEA). VAS did not differ significantly between SAPB and TEA, with a mean difference of 0.71, P = 0.08. PONV incidence did not differ significantly between SAPB and TEA (odds ratio = 0.25, P = 0.07). Hypotension incidence was lower in SAPB compared to TEA (odds ratio = 0.10, P = 0.0001). Conclusion: SAPB yielded comparable VAS with TEA in pain management of thoracic region surgery. The incidence of hypotension was lower in SAPB than in TEA. No difference in PONV incidence was observed. SAPB can be a viable alternative to TEA in thoracic region surgery.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=4;spage=329;epage=337;aulast=Suhardiepidural analgesiahypotensionnerve blocksurgeryvisual analog scale |
| spellingShingle | Lusianawati Christian Julio Suhardi Christrijogo Sumartono Citrawati Dyah Kencono Wungu Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis Tzu Chi Medical Journal epidural analgesia hypotension nerve block surgery visual analog scale |
| title | Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis |
| title_full | Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis |
| title_fullStr | Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis |
| title_full_unstemmed | Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis |
| title_short | Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis |
| title_sort | efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery systematic review and meta analysis |
| topic | epidural analgesia hypotension nerve block surgery visual analog scale |
| url | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=4;spage=329;epage=337;aulast=Suhardi |
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