Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease
Purpose. To compare central corneal thickness (CCT) values via Spectral Domain-Optical Coherence Tomography (SD-OCT) and ultrasonic pachymetry in patients with severe dry eye disease (DED) to determine the level of agreement between these 2 methods. Methods. The paired samples t-test was used to com...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/2623719 |
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| author | Ali Riza Cenk Celebi G. Ertugrul Mirza |
| author_facet | Ali Riza Cenk Celebi G. Ertugrul Mirza |
| author_sort | Ali Riza Cenk Celebi |
| collection | DOAJ |
| description | Purpose. To compare central corneal thickness (CCT) values via Spectral Domain-Optical Coherence Tomography (SD-OCT) and ultrasonic pachymetry in patients with severe dry eye disease (DED) to determine the level of agreement between these 2 methods. Methods. The paired samples t-test was used to compare CCT values in severe DED patients. Matching analysis between methods was performed using intraclass correlation coefficient (ICC). Intrasession reliability of the measurement methods was calculated via the concordance correlation coefficient (CCC), variation equivalent, and Pearson’s correlation coefficient. The Bland-Altman procedure was used to graphically represent the differences between CCT values. Results. The study included 56 eyes of 24 female and 4 male patients. Mean age of the patients was 50.9±11.3 years. Mean CCT via Cirrus SD-OCT was 523.82±30.98 μm versus 530.050±31.85 μm via ultrasonic pachymetry (paired samples t-test, P<0.001). The Bland-Altman plot showed good agreement between the examiners. The ICC for repeatability was 0.974. The CCC between the 2 methods’ CCT values was 0.973. The variation equivalent was 0.976 and Pearson’s correlation coefficient was 99.3%, which also indicated high correlation between the 2 methods’ measurements. Conclusions. The present findings show that in patients with severe DED Cirrus SD-OCT provides reliable intraobserver CCT values. |
| format | Article |
| id | doaj-art-77c76fcb3f6041cfb2a26a756b1b42ad |
| institution | OA Journals |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-77c76fcb3f6041cfb2a26a756b1b42ad2025-08-20T02:07:06ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/26237192623719Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye DiseaseAli Riza Cenk Celebi0G. Ertugrul Mirza1Department of Ophthalmology, Acibadem University School of Medicine, 34303 Istanbul, TurkeyDepartment of Ophthalmology, Erciyes University School of Medicine, 38030 Kayseri, TurkeyPurpose. To compare central corneal thickness (CCT) values via Spectral Domain-Optical Coherence Tomography (SD-OCT) and ultrasonic pachymetry in patients with severe dry eye disease (DED) to determine the level of agreement between these 2 methods. Methods. The paired samples t-test was used to compare CCT values in severe DED patients. Matching analysis between methods was performed using intraclass correlation coefficient (ICC). Intrasession reliability of the measurement methods was calculated via the concordance correlation coefficient (CCC), variation equivalent, and Pearson’s correlation coefficient. The Bland-Altman procedure was used to graphically represent the differences between CCT values. Results. The study included 56 eyes of 24 female and 4 male patients. Mean age of the patients was 50.9±11.3 years. Mean CCT via Cirrus SD-OCT was 523.82±30.98 μm versus 530.050±31.85 μm via ultrasonic pachymetry (paired samples t-test, P<0.001). The Bland-Altman plot showed good agreement between the examiners. The ICC for repeatability was 0.974. The CCC between the 2 methods’ CCT values was 0.973. The variation equivalent was 0.976 and Pearson’s correlation coefficient was 99.3%, which also indicated high correlation between the 2 methods’ measurements. Conclusions. The present findings show that in patients with severe DED Cirrus SD-OCT provides reliable intraobserver CCT values.http://dx.doi.org/10.1155/2016/2623719 |
| spellingShingle | Ali Riza Cenk Celebi G. Ertugrul Mirza Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease Journal of Ophthalmology |
| title | Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease |
| title_full | Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease |
| title_fullStr | Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease |
| title_full_unstemmed | Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease |
| title_short | Differences in Central Corneal Thickness between Spectral Domain-Optical Coherence Tomography and Ultrasound Pachymetry in Patients with Dry Eye Disease |
| title_sort | differences in central corneal thickness between spectral domain optical coherence tomography and ultrasound pachymetry in patients with dry eye disease |
| url | http://dx.doi.org/10.1155/2016/2623719 |
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