Heterocycle-based dynamic covalent chemistry for dynamic functional materials
Abstract Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic covalent chemistry can construct dynamic polymer networks, it rarely introduces other functions into polymers, whic...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59027-3 |
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| _version_ | 1850145193524723712 |
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| author | Zeyu Ma Siyu Pan Yang Yang Yuan Zeng Bo Wang Yen Wei Lei Tao |
| author_facet | Zeyu Ma Siyu Pan Yang Yang Yuan Zeng Bo Wang Yen Wei Lei Tao |
| author_sort | Zeyu Ma |
| collection | DOAJ |
| description | Abstract Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic covalent chemistry can construct dynamic polymer networks, it rarely introduces other functions into polymers, which limits the development of dynamic functional materials. Herein, we develop heterocycle-based dynamic covalent chemistry and demonstrate the reversibility of the aza-Michael addition reaction between functional heterocycle dihydropyrimidin-2(1H)-thione and electron-deficient olefins. Our method produces a degradable linear polymer and recyclable and self-healable crosslinked polymers similar to traditional dynamic covalent chemistry, but the heterocycles endow the polymer with excellent ultraviolet-blocking and high-energy blue light-blocking abilities, and tunable fluorescence and phosphorescence properties. These are difficult to create with ordinary dynamic covalent chemistry. This proof-of-concept study provides insights into heterocycle-based dynamic reactions, and may prompt the development of dynamic chemistry and dynamic functional materials. |
| format | Article |
| id | doaj-art-77bda7a7a8a245c4a057dc0a7db8bf7e |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-77bda7a7a8a245c4a057dc0a7db8bf7e2025-08-20T02:28:09ZengNature PortfolioNature Communications2041-17232025-04-0116111110.1038/s41467-025-59027-3Heterocycle-based dynamic covalent chemistry for dynamic functional materialsZeyu Ma0Siyu Pan1Yang Yang2Yuan Zeng3Bo Wang4Yen Wei5Lei Tao6The Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua UniversityThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua UniversityInstitute of Nuclear and New Energy Technology, Tsinghua UniversityThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua UniversityInstitute of Food Science and Technology, Chinese Academy of Agricultural SciencesThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua UniversityThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua UniversityAbstract Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic covalent chemistry can construct dynamic polymer networks, it rarely introduces other functions into polymers, which limits the development of dynamic functional materials. Herein, we develop heterocycle-based dynamic covalent chemistry and demonstrate the reversibility of the aza-Michael addition reaction between functional heterocycle dihydropyrimidin-2(1H)-thione and electron-deficient olefins. Our method produces a degradable linear polymer and recyclable and self-healable crosslinked polymers similar to traditional dynamic covalent chemistry, but the heterocycles endow the polymer with excellent ultraviolet-blocking and high-energy blue light-blocking abilities, and tunable fluorescence and phosphorescence properties. These are difficult to create with ordinary dynamic covalent chemistry. This proof-of-concept study provides insights into heterocycle-based dynamic reactions, and may prompt the development of dynamic chemistry and dynamic functional materials.https://doi.org/10.1038/s41467-025-59027-3 |
| spellingShingle | Zeyu Ma Siyu Pan Yang Yang Yuan Zeng Bo Wang Yen Wei Lei Tao Heterocycle-based dynamic covalent chemistry for dynamic functional materials Nature Communications |
| title | Heterocycle-based dynamic covalent chemistry for dynamic functional materials |
| title_full | Heterocycle-based dynamic covalent chemistry for dynamic functional materials |
| title_fullStr | Heterocycle-based dynamic covalent chemistry for dynamic functional materials |
| title_full_unstemmed | Heterocycle-based dynamic covalent chemistry for dynamic functional materials |
| title_short | Heterocycle-based dynamic covalent chemistry for dynamic functional materials |
| title_sort | heterocycle based dynamic covalent chemistry for dynamic functional materials |
| url | https://doi.org/10.1038/s41467-025-59027-3 |
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