Depression and Associated Factors Among Patients with Spinocerebellar Ataxia
<i>Background and Objectives:</i> Spinocerebellar ataxia (SCA) is a progressive neurodegenerative disease often accompanied by depression. This cross-sectional study investigated the prevalence of depression and the associated mental health factors in SCA patients. <i>Material and...
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2025-01-01
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| author | Sirivipa Jekpoo Nahathai Wongpakaran Tinakon Wongpakaran Chayasak Wantaneeyawong Punjaree Wiriyacosol Pised Methapatara |
| author_facet | Sirivipa Jekpoo Nahathai Wongpakaran Tinakon Wongpakaran Chayasak Wantaneeyawong Punjaree Wiriyacosol Pised Methapatara |
| author_sort | Sirivipa Jekpoo |
| collection | DOAJ |
| description | <i>Background and Objectives:</i> Spinocerebellar ataxia (SCA) is a progressive neurodegenerative disease often accompanied by depression. This cross-sectional study investigated the prevalence of depression and the associated mental health factors in SCA patients. <i>Material and Methods:</i> Eleven Thai SCA patients completed questionnaires assessing depression, anxiety, inner strengths, perceived social support, personality traits and perceived stress. <i>Results:</i> Participants’ average age was 50.27 years old. The prevalence of depression was 27.27%. Depression scores were positively correlated with OI-anxiety score (<i>r</i> = 0.887, 95%CI 0.586 to 0.968), perceived stress (<i>r</i> = 0781, 95%CI 0.305 to 0.936) and personality traits including aggression (<i>r</i> = 0.73, 95% CI 0.197 to 0.920), activity (<i>r</i> = 0.651, 95%CI 0.052 to 0.893) and neuroticism (<i>r</i> = 0.80, 95% CI 0.351 to 0.942). Conversely, depression negatively correlated with inner strengths (<i>r</i> = −0.70, 95%CI −0.910 to −0.139) and perceived social support, particularly from family (<i>r</i> = −0.88, 95%CI −0.966 to −0.564). <i>Conclusions:</i> These findings highlight the need for comprehensive mental health assessment and intervention in SCA patients. Strengthening inner strengths, promoting social support, and managing negative mental health factors may improve quality of life for patients with SCA. |
| format | Article |
| id | doaj-art-77b3050febe74efebcd062fbd65fa568 |
| institution | Kabale University |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-77b3050febe74efebcd062fbd65fa5682025-01-24T13:40:55ZengMDPI AGMedicina1010-660X1648-91442025-01-0161116010.3390/medicina61010160Depression and Associated Factors Among Patients with Spinocerebellar AtaxiaSirivipa Jekpoo0Nahathai Wongpakaran1Tinakon Wongpakaran2Chayasak Wantaneeyawong3Punjaree Wiriyacosol4Pised Methapatara5Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandSuanprug Hospital, Chang Wat Ratchaburi 70180, Thailand<i>Background and Objectives:</i> Spinocerebellar ataxia (SCA) is a progressive neurodegenerative disease often accompanied by depression. This cross-sectional study investigated the prevalence of depression and the associated mental health factors in SCA patients. <i>Material and Methods:</i> Eleven Thai SCA patients completed questionnaires assessing depression, anxiety, inner strengths, perceived social support, personality traits and perceived stress. <i>Results:</i> Participants’ average age was 50.27 years old. The prevalence of depression was 27.27%. Depression scores were positively correlated with OI-anxiety score (<i>r</i> = 0.887, 95%CI 0.586 to 0.968), perceived stress (<i>r</i> = 0781, 95%CI 0.305 to 0.936) and personality traits including aggression (<i>r</i> = 0.73, 95% CI 0.197 to 0.920), activity (<i>r</i> = 0.651, 95%CI 0.052 to 0.893) and neuroticism (<i>r</i> = 0.80, 95% CI 0.351 to 0.942). Conversely, depression negatively correlated with inner strengths (<i>r</i> = −0.70, 95%CI −0.910 to −0.139) and perceived social support, particularly from family (<i>r</i> = −0.88, 95%CI −0.966 to −0.564). <i>Conclusions:</i> These findings highlight the need for comprehensive mental health assessment and intervention in SCA patients. Strengthening inner strengths, promoting social support, and managing negative mental health factors may improve quality of life for patients with SCA.https://www.mdpi.com/1648-9144/61/1/160spinocerebellar ataxiadepressionanxietymental health |
| spellingShingle | Sirivipa Jekpoo Nahathai Wongpakaran Tinakon Wongpakaran Chayasak Wantaneeyawong Punjaree Wiriyacosol Pised Methapatara Depression and Associated Factors Among Patients with Spinocerebellar Ataxia Medicina spinocerebellar ataxia depression anxiety mental health |
| title | Depression and Associated Factors Among Patients with Spinocerebellar Ataxia |
| title_full | Depression and Associated Factors Among Patients with Spinocerebellar Ataxia |
| title_fullStr | Depression and Associated Factors Among Patients with Spinocerebellar Ataxia |
| title_full_unstemmed | Depression and Associated Factors Among Patients with Spinocerebellar Ataxia |
| title_short | Depression and Associated Factors Among Patients with Spinocerebellar Ataxia |
| title_sort | depression and associated factors among patients with spinocerebellar ataxia |
| topic | spinocerebellar ataxia depression anxiety mental health |
| url | https://www.mdpi.com/1648-9144/61/1/160 |
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