Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)

ABSTRACT Background Financial toxicity is common among families of pediatric patients with cancer. However, the availability of survey and/or screening instruments specific to pediatric family financial toxicity is limited. Methods A two‐round cross‐sectional survey was conducted in Shandong Provinc...

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Main Authors: Pengfei Li, Nan Zhang, Xinyue Xu, Yan Liu, Zhengyang Lu, Qian Gao, Shihong Lin, Weimin Guan, Wenxuan Yan, Boyu Liu, Youhua Lu, Jinming Yu
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Cancer Medicine
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Online Access:https://doi.org/10.1002/cam4.70675
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author Pengfei Li
Nan Zhang
Xinyue Xu
Yan Liu
Zhengyang Lu
Qian Gao
Shihong Lin
Weimin Guan
Wenxuan Yan
Boyu Liu
Youhua Lu
Jinming Yu
author_facet Pengfei Li
Nan Zhang
Xinyue Xu
Yan Liu
Zhengyang Lu
Qian Gao
Shihong Lin
Weimin Guan
Wenxuan Yan
Boyu Liu
Youhua Lu
Jinming Yu
author_sort Pengfei Li
collection DOAJ
description ABSTRACT Background Financial toxicity is common among families of pediatric patients with cancer. However, the availability of survey and/or screening instruments specific to pediatric family financial toxicity is limited. Methods A two‐round cross‐sectional survey was conducted in Shandong Province, China. We combined classical test theory (CTT) and item response theory (IRT) to validate items of the caregiver‐reported scale for pediatric cancer financial toxicity (CRS‐PCFT) after Delphi. The scale structure, reliability, and validity were determined and validated by exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). The threshold was discussed based on the correlations between CRS‐PCFT and socio‐factors. Findings A 16‐item initial scale was determined after Delphi. The data from 206 pilot survey samples was used to select and validate items, and a 10‐item CRS‐PCFT was developed. The scale showed satisfactory reliability and validity based on data from 398 formal survey samples. When the CRS‐PCFT scores were into high and low toxicity groups by the median, they were significantly correlated with education (r = −0.284, p < 0.0001), household income (r = −0.253, p < 0.0001), work status (r = −0.173, p = 0.001), and cancer stages (r = 0.147, p = 0.003). Interpretation CRS‐PCFT demonstrates robust reliability and validity and makes it more accurate to obtain the pediatric cancer financial toxicity conditions. Additional research should be done to validate CRS‐PCFT.
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spelling doaj-art-77ab4473a0be4f90b1dc0de91f060ef32025-08-20T03:18:05ZengWileyCancer Medicine2045-76342025-02-01144n/an/a10.1002/cam4.70675Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)Pengfei Li0Nan Zhang1Xinyue Xu2Yan Liu3Zhengyang Lu4Qian Gao5Shihong Lin6Weimin Guan7Wenxuan Yan8Boyu Liu9Youhua Lu10Jinming Yu11School of Public Health Shandong Second Medical University Weifang ChinaCancer Hospital of Shandong First Medical University (Shandong Cancer Institute, Shandong Cancer Hospital) Jinan ChinaCancer Hospital of Shandong First Medical University (Shandong Cancer Institute, Shandong Cancer Hospital) Jinan ChinaCancer Hospital of Shandong First Medical University (Shandong Cancer Institute, Shandong Cancer Hospital) Jinan ChinaSchool of Public Health Shandong Second Medical University Weifang ChinaSchool of Public Health Shandong Second Medical University Weifang ChinaSchool of Public Health Shandong Second Medical University Weifang ChinaSchool of Public Health Shandong Second Medical University Weifang ChinaSchool of Public Health Shandong Second Medical University Weifang ChinaSchool of Public Health and Health Administration, Shandong First Medical University & Shandong Academy of Medical Science Jinan ChinaCancer Hospital of Shandong First Medical University (Shandong Cancer Institute, Shandong Cancer Hospital) Jinan ChinaCancer Hospital of Shandong First Medical University (Shandong Cancer Institute, Shandong Cancer Hospital) Jinan ChinaABSTRACT Background Financial toxicity is common among families of pediatric patients with cancer. However, the availability of survey and/or screening instruments specific to pediatric family financial toxicity is limited. Methods A two‐round cross‐sectional survey was conducted in Shandong Province, China. We combined classical test theory (CTT) and item response theory (IRT) to validate items of the caregiver‐reported scale for pediatric cancer financial toxicity (CRS‐PCFT) after Delphi. The scale structure, reliability, and validity were determined and validated by exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). The threshold was discussed based on the correlations between CRS‐PCFT and socio‐factors. Findings A 16‐item initial scale was determined after Delphi. The data from 206 pilot survey samples was used to select and validate items, and a 10‐item CRS‐PCFT was developed. The scale showed satisfactory reliability and validity based on data from 398 formal survey samples. When the CRS‐PCFT scores were into high and low toxicity groups by the median, they were significantly correlated with education (r = −0.284, p < 0.0001), household income (r = −0.253, p < 0.0001), work status (r = −0.173, p = 0.001), and cancer stages (r = 0.147, p = 0.003). Interpretation CRS‐PCFT demonstrates robust reliability and validity and makes it more accurate to obtain the pediatric cancer financial toxicity conditions. Additional research should be done to validate CRS‐PCFT.https://doi.org/10.1002/cam4.70675financial toxicitypediatric cancerscale development
spellingShingle Pengfei Li
Nan Zhang
Xinyue Xu
Yan Liu
Zhengyang Lu
Qian Gao
Shihong Lin
Weimin Guan
Wenxuan Yan
Boyu Liu
Youhua Lu
Jinming Yu
Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
Cancer Medicine
financial toxicity
pediatric cancer
scale development
title Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
title_full Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
title_fullStr Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
title_full_unstemmed Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
title_short Development of A Caregiver‐Reported Scale for Pediatric Cancer Financial Toxicity (CRS‐PCFT)
title_sort development of a caregiver reported scale for pediatric cancer financial toxicity crs pcft
topic financial toxicity
pediatric cancer
scale development
url https://doi.org/10.1002/cam4.70675
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