Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants?
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by barrier dysfunction and immune dysregulation, often leading to increased allergen penetration, sensitization, and secondary infections. Colloidal oat emollients are widely used in adult AD management, but the...
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Taylor & Francis Group
2025-12-01
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| Series: | Journal of Dermatological Treatment |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/09546634.2025.2487945 |
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| author | Joseph F. Fowler Lin Ma James Bergman Paul Horowitz Tina Lavender Lawrence F. Eichenfield Zoe Draelos Simon G. Danby Michael J. Cork |
| author_facet | Joseph F. Fowler Lin Ma James Bergman Paul Horowitz Tina Lavender Lawrence F. Eichenfield Zoe Draelos Simon G. Danby Michael J. Cork |
| author_sort | Joseph F. Fowler |
| collection | DOAJ |
| description | Background Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by barrier dysfunction and immune dysregulation, often leading to increased allergen penetration, sensitization, and secondary infections. Colloidal oat emollients are widely used in adult AD management, but their role in pediatric AD treatment, prevention, and allergy modulation remains under investigation.Methods A comprehensive literature review evaluated clinical and preclinical studies on colloidal oat-containing emollients in pediatric AD treatment and prevention. Studies assessing skin barrier function, immune modulation, AD prevention, food allergy risk, and healthcare utilization were included.Results Colloidal oat emollients improved skin hydration, reduced transepidermal water loss (TEWL), and supported barrier repair, leading to fewer AD flares and reduced reliance on steroid treatments. Studies suggest that early, consistent use of advanced emollient formulations may lower AD incidence in high-risk infants and reduce food sensitization rates. Real-world data indicate that patients using colloidal oat emollients have fewer clinic visits and lower overall healthcare costs. Concerns about oat sensitization remain unsubstantiated in most studies.Conclusion Colloidal oat emollients are effective, well-tolerated, and cost-efficient for pediatric AD management. Their barrier-restorative and anti-inflammatory properties may reduce AD and allergy risk. Future research should focus on head-to-head emollient comparisons to optimize treatment strategies. |
| format | Article |
| id | doaj-art-77a9f891e09147bb87552ee10c4eac76 |
| institution | OA Journals |
| issn | 0954-6634 1471-1753 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj-art-77a9f891e09147bb87552ee10c4eac762025-08-20T02:34:46ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532025-12-0136110.1080/09546634.2025.2487945Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants?Joseph F. Fowler0Lin Ma1James Bergman2Paul Horowitz3Tina Lavender4Lawrence F. Eichenfield5Zoe Draelos6Simon G. Danby7Michael J. Cork8Dermatology, University of Louisville School of Medicine, Louisville, Kentucky, USADermatology, Beijing Children’s Hospital, Beijing, ChinaDermatology, Bellevue, Washington, USAPediatrician, Children’s Hospital of Los Angeles, Los Angeles, California, USACentre for Childbirth, Women’s and Newborn Health Liverpool School of Tropical Medicine, Liverpool, UKDepartments of Dermatology and Pediatrics, University of California, San Diego and Rady Children’s Hospital, San Diego, California, USADermatology North Carolina, High Point, North Carolina, USASheffield Dermatology Research, Division of Clinical Medicine, University of Sheffield Medical School, Sheffield, UKSheffield Dermatology Research, University of Sheffield, Sheffield Children’s Hospital, Sheffield, UKBackground Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by barrier dysfunction and immune dysregulation, often leading to increased allergen penetration, sensitization, and secondary infections. Colloidal oat emollients are widely used in adult AD management, but their role in pediatric AD treatment, prevention, and allergy modulation remains under investigation.Methods A comprehensive literature review evaluated clinical and preclinical studies on colloidal oat-containing emollients in pediatric AD treatment and prevention. Studies assessing skin barrier function, immune modulation, AD prevention, food allergy risk, and healthcare utilization were included.Results Colloidal oat emollients improved skin hydration, reduced transepidermal water loss (TEWL), and supported barrier repair, leading to fewer AD flares and reduced reliance on steroid treatments. Studies suggest that early, consistent use of advanced emollient formulations may lower AD incidence in high-risk infants and reduce food sensitization rates. Real-world data indicate that patients using colloidal oat emollients have fewer clinic visits and lower overall healthcare costs. Concerns about oat sensitization remain unsubstantiated in most studies.Conclusion Colloidal oat emollients are effective, well-tolerated, and cost-efficient for pediatric AD management. Their barrier-restorative and anti-inflammatory properties may reduce AD and allergy risk. Future research should focus on head-to-head emollient comparisons to optimize treatment strategies.https://www.tandfonline.com/doi/10.1080/09546634.2025.2487945Colloidal oatatopic dermatitisinfantatopic dermatitis in infantscolloidal oat emollientprevention of atopic dermatitis |
| spellingShingle | Joseph F. Fowler Lin Ma James Bergman Paul Horowitz Tina Lavender Lawrence F. Eichenfield Zoe Draelos Simon G. Danby Michael J. Cork Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? Journal of Dermatological Treatment Colloidal oat atopic dermatitis infant atopic dermatitis in infants colloidal oat emollient prevention of atopic dermatitis |
| title | Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? |
| title_full | Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? |
| title_fullStr | Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? |
| title_full_unstemmed | Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? |
| title_short | Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? |
| title_sort | is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants |
| topic | Colloidal oat atopic dermatitis infant atopic dermatitis in infants colloidal oat emollient prevention of atopic dermatitis |
| url | https://www.tandfonline.com/doi/10.1080/09546634.2025.2487945 |
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