Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii
Ventilator-associated pneumonia (VAP) is a common and serious complication in critically ill patients, particularly those requiring prolonged mechanical ventilation. Extensively drug-resistant (XDR) Acinetobacter baumannii has emerged as a significant threat in VAP cases, complicating treatment due...
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| Language: | English |
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Open Exploration Publishing Inc.
2025-01-01
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| Series: | Exploration of Medicine |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A1001271/1001271.pdf |
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| author | Amit Kumar Rajesh Chetiwal Neha Rana Aman Dubey Shweta Tanwar |
| author_facet | Amit Kumar Rajesh Chetiwal Neha Rana Aman Dubey Shweta Tanwar |
| author_sort | Amit Kumar |
| collection | DOAJ |
| description | Ventilator-associated pneumonia (VAP) is a common and serious complication in critically ill patients, particularly those requiring prolonged mechanical ventilation. Extensively drug-resistant (XDR) Acinetobacter baumannii has emerged as a significant threat in VAP cases, complicating treatment due to its exceptionally high level of antibiotic resistance. We present a case of a 62-year-old male patient with severe acute ischemic stroke, who developed VAP during his stay in the intensive care unit (ICU). Cultures confirmed XDR Acinetobacter baumannii as the causative organism. The infection was further complicated by the development of a lung abscess, a rare but severe consequence of VAP. The patient was treated with a targeted antimicrobial regimen consisting of colistin, vancomycin, and tigecycline. Despite the pathogen’s resistance profile, the patient’s infection showed gradual improvement with sustained treatment. However, the recovery process was significantly prolonged due to the complexity of the infection, necessitating extended supportive care during hospitalization. This case highlights the challenges posed by XDR infections in critically ill patients and the importance of a tailored antimicrobial approach to effectively manage severe complications such as lung abscess. |
| format | Article |
| id | doaj-art-77a8a9d4d3f6408b8e94530dcced6864 |
| institution | Kabale University |
| issn | 2692-3106 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Medicine |
| spelling | doaj-art-77a8a9d4d3f6408b8e94530dcced68642025-01-14T07:15:11ZengOpen Exploration Publishing Inc.Exploration of Medicine2692-31062025-01-016100127110.37349/emed.2025.1001271Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumanniiAmit Kumar0https://orcid.org/0000-0001-9348-7601Rajesh Chetiwal1https://orcid.org/0000-0001-6570-8577Neha Rana2Aman Dubey3Shweta Tanwar4Department of Medicine, ESIC Postgraduate Institute Medical Sciences and Research, New Delhi 110015, IndiaDepartment of Medicine, ESIC Postgraduate Institute Medical Sciences and Research, New Delhi 110015, IndiaDepartment of Medicine, ESIC Postgraduate Institute Medical Sciences and Research, New Delhi 110015, IndiaDepartment of Medicine, ESIC Postgraduate Institute Medical Sciences and Research, New Delhi 110015, IndiaIndian Council of Medical Research, New Delhi 110029, IndiaVentilator-associated pneumonia (VAP) is a common and serious complication in critically ill patients, particularly those requiring prolonged mechanical ventilation. Extensively drug-resistant (XDR) Acinetobacter baumannii has emerged as a significant threat in VAP cases, complicating treatment due to its exceptionally high level of antibiotic resistance. We present a case of a 62-year-old male patient with severe acute ischemic stroke, who developed VAP during his stay in the intensive care unit (ICU). Cultures confirmed XDR Acinetobacter baumannii as the causative organism. The infection was further complicated by the development of a lung abscess, a rare but severe consequence of VAP. The patient was treated with a targeted antimicrobial regimen consisting of colistin, vancomycin, and tigecycline. Despite the pathogen’s resistance profile, the patient’s infection showed gradual improvement with sustained treatment. However, the recovery process was significantly prolonged due to the complexity of the infection, necessitating extended supportive care during hospitalization. This case highlights the challenges posed by XDR infections in critically ill patients and the importance of a tailored antimicrobial approach to effectively manage severe complications such as lung abscess.https://www.explorationpub.com/uploads/Article/A1001271/1001271.pdfventilator-associated pneumonia (vap)critically illacinetobacter baumanniilung abscess |
| spellingShingle | Amit Kumar Rajesh Chetiwal Neha Rana Aman Dubey Shweta Tanwar Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii Exploration of Medicine ventilator-associated pneumonia (vap) critically ill acinetobacter baumannii lung abscess |
| title | Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii |
| title_full | Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii |
| title_fullStr | Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii |
| title_full_unstemmed | Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii |
| title_short | Lung abscess complicating ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii |
| title_sort | lung abscess complicating ventilator associated pneumonia caused by extensively drug resistant acinetobacter baumannii |
| topic | ventilator-associated pneumonia (vap) critically ill acinetobacter baumannii lung abscess |
| url | https://www.explorationpub.com/uploads/Article/A1001271/1001271.pdf |
| work_keys_str_mv | AT amitkumar lungabscesscomplicatingventilatorassociatedpneumoniacausedbyextensivelydrugresistantacinetobacterbaumannii AT rajeshchetiwal lungabscesscomplicatingventilatorassociatedpneumoniacausedbyextensivelydrugresistantacinetobacterbaumannii AT neharana lungabscesscomplicatingventilatorassociatedpneumoniacausedbyextensivelydrugresistantacinetobacterbaumannii AT amandubey lungabscesscomplicatingventilatorassociatedpneumoniacausedbyextensivelydrugresistantacinetobacterbaumannii AT shwetatanwar lungabscesscomplicatingventilatorassociatedpneumoniacausedbyextensivelydrugresistantacinetobacterbaumannii |