[<sup>18</sup>F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana

[<sup>18</sup>F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana

We present an <sup>18</sup>F-fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing m...

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Bibliographic Details
Main Authors: Tilman Speicher, Moritz B. Bastian, Konstantinos Christofyllakis, Florian Rosar, Samer Ezziddin, Caroline Burgard
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Diagnostics
Subjects:
Langerhans cell histiocytosis
FDG
PET/CT
glucose metabolism
Online Access:https://www.mdpi.com/2075-4418/15/7/862
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Summary:We present an <sup>18</sup>F-fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing multiple FDG-avid osteolytic lesions of the axial skeleton including a vertebra plana of T7 and paraosseous soft tissue lesions. A CT-guided biopsy confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case highlights the importance of considering LCH in young patients with vertebral collapse and underscores the role of PET/CT imaging in establishing an accurate diagnosis.
ISSN:2075-4418

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