Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.

Whether codon usage fine-tunes mRNA translation in mammals remains controversial, with recent papers suggesting that production of proteins in specific Gene Ontological (GO) pathways can be regulated by actively modifying the codon and anticodon pools in different cellular conditions. In this work,...

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Main Authors: Konrad L M Rudolph, Bianca M Schmitt, Diego Villar, Robert J White, John C Marioni, Claudia Kutter, Duncan T Odom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006024&type=printable
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