Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics

<b>Background</b>: The growing demand for innovative biomaterials with antimicrobial properties has driven research into natural and synthetic compounds, such as propolis and nanosilver, known for their antimicrobial efficacy. <b>Methods</b>: This study uses Google Trends dat...

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Main Authors: Magdalena Sycińska-Dziarnowska, Liliana Szyszka-Sommerfeld, Krzysztof Woźniak, Gianrico Spagnuolo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Dentistry Journal
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Online Access:https://www.mdpi.com/2304-6767/13/6/253
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author Magdalena Sycińska-Dziarnowska
Liliana Szyszka-Sommerfeld
Krzysztof Woźniak
Gianrico Spagnuolo
author_facet Magdalena Sycińska-Dziarnowska
Liliana Szyszka-Sommerfeld
Krzysztof Woźniak
Gianrico Spagnuolo
author_sort Magdalena Sycińska-Dziarnowska
collection DOAJ
description <b>Background</b>: The growing demand for innovative biomaterials with antimicrobial properties has driven research into natural and synthetic compounds, such as propolis and nanosilver, known for their antimicrobial efficacy. <b>Methods</b>: This study uses Google Trends data to analyze global search interest in five key terms—<i>propolis</i>, <i>antimicrobial</i>, <i>antibacterial</i>, <i>nanosilver</i>, and <i>biomaterials</i>—over a ten-year period (starting November 2014). The objective is to evaluate temporal variations, quantify correlations between the terms, and explore how external events, such as the COVID-19 pandemic, have influenced public and clinical interest in these topics. Search data were extracted, normalized, and analyzed using multivariate time series methods, including vector autoregression (VAR) modeling, Impulse Response Function (IRF) analysis, and forecast error variance decomposition (FEVD). Stability, causality, and inter-period relationships were assessed using statistical analysis, with results visualized through time series plots and impulse response coefficients. <b>Results</b>: Key findings reveal significant interdependencies between search terms, with surges in one often resulting in immediate or short-term increases in others. Notable trends include a marked increase in COVID-19 interest for <i>nanosilver</i>, <i>propolis</i>, and <i>antibacterial</i>, followed by a return to baseline levels, while <i>antimicrobial</i> maintained a sustained upward trajectory. <i>Biomaterials</i> experienced initial declines but later stabilized at elevated levels. <b>Conclusions</b>: These findings underscore the oscillating nature of public interest in antimicrobial and biomaterial innovations, highlighting opportunities for targeted research and commercialization. By adapting future material development to emerging trends and clinical needs, dentistry can use these insights to develop infection control strategies, improve restorative materials, and deal with persistent challenges such as antimicrobial resistance, peri-implantitis, and tooth caries treatment.
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publishDate 2025-06-01
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series Dentistry Journal
spelling doaj-art-77998eb946b94aef829c81eb4f7ca8f82025-08-20T03:27:10ZengMDPI AGDentistry Journal2304-67672025-06-0113625310.3390/dj13060253Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data AnalyticsMagdalena Sycińska-Dziarnowska0Liliana Szyszka-Sommerfeld1Krzysztof Woźniak2Gianrico Spagnuolo3Department of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandDepartment of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandDepartment of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, 80131 Napoli, Italy<b>Background</b>: The growing demand for innovative biomaterials with antimicrobial properties has driven research into natural and synthetic compounds, such as propolis and nanosilver, known for their antimicrobial efficacy. <b>Methods</b>: This study uses Google Trends data to analyze global search interest in five key terms—<i>propolis</i>, <i>antimicrobial</i>, <i>antibacterial</i>, <i>nanosilver</i>, and <i>biomaterials</i>—over a ten-year period (starting November 2014). The objective is to evaluate temporal variations, quantify correlations between the terms, and explore how external events, such as the COVID-19 pandemic, have influenced public and clinical interest in these topics. Search data were extracted, normalized, and analyzed using multivariate time series methods, including vector autoregression (VAR) modeling, Impulse Response Function (IRF) analysis, and forecast error variance decomposition (FEVD). Stability, causality, and inter-period relationships were assessed using statistical analysis, with results visualized through time series plots and impulse response coefficients. <b>Results</b>: Key findings reveal significant interdependencies between search terms, with surges in one often resulting in immediate or short-term increases in others. Notable trends include a marked increase in COVID-19 interest for <i>nanosilver</i>, <i>propolis</i>, and <i>antibacterial</i>, followed by a return to baseline levels, while <i>antimicrobial</i> maintained a sustained upward trajectory. <i>Biomaterials</i> experienced initial declines but later stabilized at elevated levels. <b>Conclusions</b>: These findings underscore the oscillating nature of public interest in antimicrobial and biomaterial innovations, highlighting opportunities for targeted research and commercialization. By adapting future material development to emerging trends and clinical needs, dentistry can use these insights to develop infection control strategies, improve restorative materials, and deal with persistent challenges such as antimicrobial resistance, peri-implantitis, and tooth caries treatment.https://www.mdpi.com/2304-6767/13/6/253nanosilverpropolisantibacterialantimicrobialGoogle Trends
spellingShingle Magdalena Sycińska-Dziarnowska
Liliana Szyszka-Sommerfeld
Krzysztof Woźniak
Gianrico Spagnuolo
Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
Dentistry Journal
nanosilver
propolis
antibacterial
antimicrobial
Google Trends
title Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
title_full Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
title_fullStr Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
title_full_unstemmed Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
title_short Exploring Global Interest in Propolis, Nanosilver, and Biomaterials: Insights and Implications for Dentistry from Big Data Analytics
title_sort exploring global interest in propolis nanosilver and biomaterials insights and implications for dentistry from big data analytics
topic nanosilver
propolis
antibacterial
antimicrobial
Google Trends
url https://www.mdpi.com/2304-6767/13/6/253
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