Endoscopic diagnosis and management of eosinophilic esophagitis
Abstract Eosinophilic esophagitis is a chronic allergic inflammatory disease, and its incidence and prevalence have recently increased. Eosinophilic esophagitis has not become a rare disease; thus, knowledge for diagnosing it is needed in current clinical practice. The adequate management of endosco...
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| Format: | Article |
| Language: | English |
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Wiley
2025-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.70063 |
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| author | Fumio Tanaka Akinari Sawada Sayaka Tanaka Kenichi Kohashi Yasuhiro Fujiwara |
| author_facet | Fumio Tanaka Akinari Sawada Sayaka Tanaka Kenichi Kohashi Yasuhiro Fujiwara |
| author_sort | Fumio Tanaka |
| collection | DOAJ |
| description | Abstract Eosinophilic esophagitis is a chronic allergic inflammatory disease, and its incidence and prevalence have recently increased. Eosinophilic esophagitis has not become a rare disease; thus, knowledge for diagnosing it is needed in current clinical practice. The adequate management of endoscopic procedures is particularly important for the diagnosis and evaluation of inflammatory activity and therapeutic responses. The therapeutic options for eosinophilic esophagitis include anti‐acid drugs such as proton pump inhibitors, potassium‐competitive acid blockers, swallowed topical corticosteroids, biologics, and dietary elimination therapies. Moreover, endoscopic esophageal dilation is a therapeutic option for fibrotic strictures due to eosinophilic esophagitis to improve obstructive symptoms, such as dysphagia and food impaction. In this review, we describe the endoscopic characteristics of eosinophilic esophagitis, including an endoscopic reference score and an optimal biopsy protocol to diagnose and evaluate the therapeutic response. We also describe a current therapeutic management of eosinophilic esophagitis. |
| format | Article |
| id | doaj-art-779935a9311443cd909b17b98dbdfa5e |
| institution | OA Journals |
| issn | 2692-4609 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-779935a9311443cd909b17b98dbdfa5e2025-08-20T02:18:56ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.70063Endoscopic diagnosis and management of eosinophilic esophagitisFumio Tanaka0Akinari Sawada1Sayaka Tanaka2Kenichi Kohashi3Yasuhiro Fujiwara4Department of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka JapanDepartment of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka JapanDepartment of Pathology Graduate School of Medicine Osaka Metropolitan University Osaka JapanDepartment of Pathology Graduate School of Medicine Osaka Metropolitan University Osaka JapanDepartment of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka JapanAbstract Eosinophilic esophagitis is a chronic allergic inflammatory disease, and its incidence and prevalence have recently increased. Eosinophilic esophagitis has not become a rare disease; thus, knowledge for diagnosing it is needed in current clinical practice. The adequate management of endoscopic procedures is particularly important for the diagnosis and evaluation of inflammatory activity and therapeutic responses. The therapeutic options for eosinophilic esophagitis include anti‐acid drugs such as proton pump inhibitors, potassium‐competitive acid blockers, swallowed topical corticosteroids, biologics, and dietary elimination therapies. Moreover, endoscopic esophageal dilation is a therapeutic option for fibrotic strictures due to eosinophilic esophagitis to improve obstructive symptoms, such as dysphagia and food impaction. In this review, we describe the endoscopic characteristics of eosinophilic esophagitis, including an endoscopic reference score and an optimal biopsy protocol to diagnose and evaluate the therapeutic response. We also describe a current therapeutic management of eosinophilic esophagitis.https://doi.org/10.1002/deo2.70063diagnosisendoscopyeosinophilic esophagitiseosinophilstherapeutics |
| spellingShingle | Fumio Tanaka Akinari Sawada Sayaka Tanaka Kenichi Kohashi Yasuhiro Fujiwara Endoscopic diagnosis and management of eosinophilic esophagitis DEN Open diagnosis endoscopy eosinophilic esophagitis eosinophils therapeutics |
| title | Endoscopic diagnosis and management of eosinophilic esophagitis |
| title_full | Endoscopic diagnosis and management of eosinophilic esophagitis |
| title_fullStr | Endoscopic diagnosis and management of eosinophilic esophagitis |
| title_full_unstemmed | Endoscopic diagnosis and management of eosinophilic esophagitis |
| title_short | Endoscopic diagnosis and management of eosinophilic esophagitis |
| title_sort | endoscopic diagnosis and management of eosinophilic esophagitis |
| topic | diagnosis endoscopy eosinophilic esophagitis eosinophils therapeutics |
| url | https://doi.org/10.1002/deo2.70063 |
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