Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty
Drug-coated balloons have emerged as effective therapy for treating in-stent restenosis and de novo lesions. The animal studies have shown the mechanism of action of paclitaxel-coated balloon in coronary arteries which leads to medial necrosis that may explain the better angiographic remodelling obs...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | JACC: Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666084925006692 |
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| author | Aninka Saboe, MD Chetan Upadhya, MD Aloke Finn, MD Sandeep Basavarajaiah, MD |
| author_facet | Aninka Saboe, MD Chetan Upadhya, MD Aloke Finn, MD Sandeep Basavarajaiah, MD |
| author_sort | Aninka Saboe, MD |
| collection | DOAJ |
| description | Drug-coated balloons have emerged as effective therapy for treating in-stent restenosis and de novo lesions. The animal studies have shown the mechanism of action of paclitaxel-coated balloon in coronary arteries which leads to medial necrosis that may explain the better angiographic remodelling observed with paclitaxel- as compared to sirolimus-coated balloons. However, in some cases, paclitaxel may cause adverse remodelling resulting in coronary artery aneurysm. Here, we report 4 cases of coronary artery aneurysm post paclitaxel-coated balloon angioplasty and discuss its possible mechanism, management, and potential implications for future practice. |
| format | Article |
| id | doaj-art-778e49fd024a463a9f99f19c8a72a0a4 |
| institution | Kabale University |
| issn | 2666-0849 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Case Reports |
| spelling | doaj-art-778e49fd024a463a9f99f19c8a72a0a42025-08-20T03:29:34ZengElsevierJACC: Case Reports2666-08492025-07-01301710389110.1016/j.jaccas.2025.103891Coronary Artery Aneurysm Post Drug-Coated Balloon AngioplastyAninka Saboe, MD0Chetan Upadhya, MD1Aloke Finn, MD2Sandeep Basavarajaiah, MD3Universitas Padjadjaran–Hasan Sadikin General Hospital, IndonesiaGlan Clwyd Hospital, Bodelwyddan, Denbigshire, North Wales, United KingdomCVPath Institute, Gaithersburg, Maryland, USAHeartlands Hospital, University Hospital Birmingham, United Kingdom; Address for correspondence: Dr Sandeep Basavarajaiah, Heartlands Hospital, Birmingham B9 5SS, United Kingdom.Drug-coated balloons have emerged as effective therapy for treating in-stent restenosis and de novo lesions. The animal studies have shown the mechanism of action of paclitaxel-coated balloon in coronary arteries which leads to medial necrosis that may explain the better angiographic remodelling observed with paclitaxel- as compared to sirolimus-coated balloons. However, in some cases, paclitaxel may cause adverse remodelling resulting in coronary artery aneurysm. Here, we report 4 cases of coronary artery aneurysm post paclitaxel-coated balloon angioplasty and discuss its possible mechanism, management, and potential implications for future practice.http://www.sciencedirect.com/science/article/pii/S2666084925006692acute coronary syndromedrug-coated balloonpercutaneous coronary intervention |
| spellingShingle | Aninka Saboe, MD Chetan Upadhya, MD Aloke Finn, MD Sandeep Basavarajaiah, MD Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty JACC: Case Reports acute coronary syndrome drug-coated balloon percutaneous coronary intervention |
| title | Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty |
| title_full | Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty |
| title_fullStr | Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty |
| title_full_unstemmed | Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty |
| title_short | Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty |
| title_sort | coronary artery aneurysm post drug coated balloon angioplasty |
| topic | acute coronary syndrome drug-coated balloon percutaneous coronary intervention |
| url | http://www.sciencedirect.com/science/article/pii/S2666084925006692 |
| work_keys_str_mv | AT aninkasaboemd coronaryarteryaneurysmpostdrugcoatedballoonangioplasty AT chetanupadhyamd coronaryarteryaneurysmpostdrugcoatedballoonangioplasty AT alokefinnmd coronaryarteryaneurysmpostdrugcoatedballoonangioplasty AT sandeepbasavarajaiahmd coronaryarteryaneurysmpostdrugcoatedballoonangioplasty |