Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Abstract Testis-specific transcript 10 (Tex10) is highly expressed in the testis, embryonic stem cells (ESCs), and primordial germ cells (PGCs). We previously generated a Tex10 knockout mouse model demonstrating its critical roles in ESC pluripotency and preimplantation development. Here, using cond...

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Bibliographic Details
Main Authors: Feifei Yuan, Jihong Yang, Fanglin Ma, Zhe Hu, Vikas Malik, Ruge Zang, Dan Li, Xianle Shi, Xin Huang, Hongwei Zhou, Jianlong Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57165-2
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