Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?

Background. The study aims to verify if the time of preoperative stabilization (≤24 or >24 hours) could be predictive for the severity of clinical condition among patients affected by congenital diaphragmatic hernia. Methods. 55 of the 73 patients enrolled in the study achieved presurgical stabil...

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Main Authors: Andrea Gentili, Rosina De Rose, Elisa Iannella, Maria Letizia Bacchi Reggiani, Mario Lima, Simonetta Baroncini
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2012/402170
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author Andrea Gentili
Rosina De Rose
Elisa Iannella
Maria Letizia Bacchi Reggiani
Mario Lima
Simonetta Baroncini
author_facet Andrea Gentili
Rosina De Rose
Elisa Iannella
Maria Letizia Bacchi Reggiani
Mario Lima
Simonetta Baroncini
author_sort Andrea Gentili
collection DOAJ
description Background. The study aims to verify if the time of preoperative stabilization (≤24 or >24 hours) could be predictive for the severity of clinical condition among patients affected by congenital diaphragmatic hernia. Methods. 55 of the 73 patients enrolled in the study achieved presurgical stabilization and underwent surgical correction. Respiratory and hemodynamic indexes, postnatal scores, the need for advanced respiratory support, the length of HFOV, tracheal intubation, PICU, and hospital stay were compared between patients reaching stabilization in ≤24 or >24 hours. Results. Both groups had a 100% survival rate. Neonates stabilized in ≤24 hours are more regular in the postoperative period and had an easier intensive care path; those taking >24 hours showed more complications and their care path was longer and more complex. Conclusions. The length of preoperative stabilization does not affect mortality, but is a valid parameter to identify difficulties in survivors’ clinical pathway.
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spelling doaj-art-777edcff52e2494cb617eacbc0e33d882025-02-03T01:21:16ZengWileyInternational Journal of Pediatrics1687-97401687-97592012-01-01201210.1155/2012/402170402170Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?Andrea Gentili0Rosina De Rose1Elisa Iannella2Maria Letizia Bacchi Reggiani3Mario Lima4Simonetta Baroncini5Department of Paediatric Anaesthesia and Intensive Care, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyDepartment of Paediatric Anaesthesia and Intensive Care, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyDepartment of Paediatric Anaesthesia and Intensive Care, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyDepartment of Cardiology, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyDepartment of Surgical Paediatrics, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyDepartment of Paediatric Anaesthesia and Intensive Care, S. Orsola-Malpighi Hospital, University of Bologna, 40183 Bologna, ItalyBackground. The study aims to verify if the time of preoperative stabilization (≤24 or >24 hours) could be predictive for the severity of clinical condition among patients affected by congenital diaphragmatic hernia. Methods. 55 of the 73 patients enrolled in the study achieved presurgical stabilization and underwent surgical correction. Respiratory and hemodynamic indexes, postnatal scores, the need for advanced respiratory support, the length of HFOV, tracheal intubation, PICU, and hospital stay were compared between patients reaching stabilization in ≤24 or >24 hours. Results. Both groups had a 100% survival rate. Neonates stabilized in ≤24 hours are more regular in the postoperative period and had an easier intensive care path; those taking >24 hours showed more complications and their care path was longer and more complex. Conclusions. The length of preoperative stabilization does not affect mortality, but is a valid parameter to identify difficulties in survivors’ clinical pathway.http://dx.doi.org/10.1155/2012/402170
spellingShingle Andrea Gentili
Rosina De Rose
Elisa Iannella
Maria Letizia Bacchi Reggiani
Mario Lima
Simonetta Baroncini
Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
International Journal of Pediatrics
title Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
title_full Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
title_fullStr Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
title_full_unstemmed Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
title_short Is the Time Necessary to Obtain Preoperative Stabilization a Predictive Index of Outcome in Neonatal Congenital Diaphragmatic Hernia?
title_sort is the time necessary to obtain preoperative stabilization a predictive index of outcome in neonatal congenital diaphragmatic hernia
url http://dx.doi.org/10.1155/2012/402170
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