Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes
Background: Propionibacterium acnes is a bacterium found on the skin that plays a significant role in acne vulgaris. The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. One such plant is jambl...
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| Format: | Article |
| Language: | English |
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Indonesian Society for Biochemistry and Molecular Biology
2024-07-01
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| Series: | Acta Biochimica Indonesiana |
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| Online Access: | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/161 |
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| author | Maria Fransiska Priska Yulianti Anita Lidesna Shinta Amat Regina Marvina Hutasoit Prisca Deviani Pakan |
| author_facet | Maria Fransiska Priska Yulianti Anita Lidesna Shinta Amat Regina Marvina Hutasoit Prisca Deviani Pakan |
| author_sort | Maria Fransiska Priska Yulianti |
| collection | DOAJ |
| description |
Background: Propionibacterium acnes is a bacterium found on the skin that plays a significant role in acne vulgaris. The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. One such plant is jamblang (Syzygium cumini), which has demonstrated antibacterial properties.
Objective: This research aims to test the antibacterial activity of jamblang leaf extract against the growth of P. acnes.
Method: The study employed an experimental design with a posttest-only control group design. The treatment groups consisted of a positive control (clindamycin), a negative control (sterile distilled water), and jamblang leaf extract groups with concentrations of 100%, 50%, 25%, 12.5%, and 6.25% (n=4). Data analysis was conducted using the One-Way ANOVA statistical test.
Results: The jamblang leaf extract exhibited antibacterial potential against the growth of P. acnes. The extract showed strong antibacterial activity at concentrations of 100%, 50%, 25%, and 12.5%, and moderate antibacterial activity at a concentration of 6.25%.
Conclusion: This suggests that jamblang leaf extract could be a promising alternative therapy for treating acne vulgaris, offering a natural solution to combat antibiotic resistance.
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| format | Article |
| id | doaj-art-776efea191224069a034ea70d74987cb |
| institution | Kabale University |
| issn | 2654-6108 2654-3222 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Indonesian Society for Biochemistry and Molecular Biology |
| record_format | Article |
| series | Acta Biochimica Indonesiana |
| spelling | doaj-art-776efea191224069a034ea70d74987cb2025-02-08T03:04:50ZengIndonesian Society for Biochemistry and Molecular BiologyActa Biochimica Indonesiana2654-61082654-32222024-07-016210.32889/actabiona.161Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnesMaria Fransiska Priska Yulianti0Anita Lidesna Shinta Amat1Regina Marvina Hutasoit2Prisca Deviani Pakan3Medicine Program, Faculty of Medicine and Veterinary Science, Universitas Nusa Cendana, Kupang City, 85001, IndonesiaDepartment of Biomedicine of Medicine Program, Faculty of Medicine and Veterinary Science, Universitas Nusa Cendana, Kupang City, 85001, IndonesiaDepartment of Biomedicine of Medicine Program, Faculty of Medicine and Veterinary Science, Universitas Nusa Cendana, Kupang City, 85001, IndonesiaDepartment of Pharmacology of Pharmacy Program, Faculty of Medicine and Veterinary Medicine, Unversitas Nusa Cendana, 85001, Indonesia Background: Propionibacterium acnes is a bacterium found on the skin that plays a significant role in acne vulgaris. The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. One such plant is jamblang (Syzygium cumini), which has demonstrated antibacterial properties. Objective: This research aims to test the antibacterial activity of jamblang leaf extract against the growth of P. acnes. Method: The study employed an experimental design with a posttest-only control group design. The treatment groups consisted of a positive control (clindamycin), a negative control (sterile distilled water), and jamblang leaf extract groups with concentrations of 100%, 50%, 25%, 12.5%, and 6.25% (n=4). Data analysis was conducted using the One-Way ANOVA statistical test. Results: The jamblang leaf extract exhibited antibacterial potential against the growth of P. acnes. The extract showed strong antibacterial activity at concentrations of 100%, 50%, 25%, and 12.5%, and moderate antibacterial activity at a concentration of 6.25%. Conclusion: This suggests that jamblang leaf extract could be a promising alternative therapy for treating acne vulgaris, offering a natural solution to combat antibiotic resistance. https://pbbmi.org/newjurnal/index.php/actabioina/article/view/161acne vulgarisantibacterial activityjamblang leaf extractPropionibacterium acnesSyzygium cumini |
| spellingShingle | Maria Fransiska Priska Yulianti Anita Lidesna Shinta Amat Regina Marvina Hutasoit Prisca Deviani Pakan Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes Acta Biochimica Indonesiana acne vulgaris antibacterial activity jamblang leaf extract Propionibacterium acnes Syzygium cumini |
| title | Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes |
| title_full | Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes |
| title_fullStr | Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes |
| title_full_unstemmed | Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes |
| title_short | Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes |
| title_sort | antibacterial activity of jamblang leaf ethanol extract syzygium cumini against the growth of propionibacterium acnes |
| topic | acne vulgaris antibacterial activity jamblang leaf extract Propionibacterium acnes Syzygium cumini |
| url | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/161 |
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